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关于此项目
线性分子式:
NH2(CH2)4NH2 · 2HCl
化学文摘社编号:
分子量:
161.07
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
206-375-9
MDL number:
Beilstein/REAXYS Number:
3906680
产品名称
腐胺 二盐酸盐, ≥98% (TLC)
Quality Level
assay
≥98% (TLC)
form
powder
mp
280 °C (dec.) (lit.)
solubility
H2O: soluble 100 mg/mL, clear, colorless
SMILES string
Cl[H].Cl[H].NCCCCN
InChI
1S/C4H12N2.2ClH/c5-3-1-2-4-6;;/h1-6H2;2*1H
InChI key
XXWCODXIQWIHQN-UHFFFAOYSA-N
Application
腐胺二盐酸盐已用于:
- 作为高效液相色谱(HPLC)的生物活性胺标准品
- 作为杜氏改良Eagle培养基(DMEM)的激素混合物添加剂组分,研究其对神经干细胞的影响
- 作为用于子宮內膜癌细胞培养的DMEM培养基的补充剂
Biochem/physiol Actions
结合到 NMDA 受体的聚胺调控位点并增强 NMDA 感应电流;亚精胺的前体。
结合到 NMDA 受体的聚胺调控位点;增强 NMDA 感应电流。
腐胺是一种带正电荷的脂肪胺。可用作精胺前体,在聚胺生物合成中发挥作用。腐胺存在于几种植物、动物和细菌中。它在大肠杆菌细胞的增殖和生长中起作用。腐胺可用作农药、表面活性剂、药物、聚合物和添加剂中的组分。
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 1
flash_point_f
113.0 °F - closed cup
flash_point_c
45 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
Mito Kanatsu-Shinohara et al.
Methods in enzymology, 477, 17-36 (2010-08-12)
Spermatogonial stem cells (SSCs) in the testes are a new target for germline modification. With the development of an in vitro culture system and spermatogonial transplantation technique, SSCs can now be manipulated and used as an alternative to embryonic stem
Ulises Gómez-Pinedo et al.
Frontiers in neurology, 8, 255-255 (2017-06-22)
Alexander disease (AxD) is a rare disease caused by mutations in the gene encoding glial fibrillary acidic protein (GFAP). The disease is characterized by presence of GFAP aggregates in the cytoplasm of astrocytes and loss of myelin. Determine the effect
Jian Liu et al.
Journal of neuroscience research, 98(7), 1498-1513 (2020-03-14)
The neuroretina is protected by its own defense system, that is microglia and the complement system. Under normal physiological conditions, microglial activation is tightly regulated by the neurons although the underlying mechanism remains elusive. Using published single-cell RNA sequencing data
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P7505-25G | 04061835558643 |
| P7505-100G | 04061835558636 |

