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Merck
CN

P7633

磷脂酶C 来源于产气荚膜梭菌(韦氏梭菌)

greener alternative

Type I, lyophilized powder, 10-50 units/mg protein

别名:

PC-PLC, 卵磷脂酶 C, 磷脂二酯酶 I, 磷脂酰胆碱胆碱磷酸水解酶

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关于此项目

化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-638-2
MDL number:
Specific activity:
10-50 units/mg protein
Biological source:
bacterial (Clostridium perfringens)
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biological source

bacterial (Clostridium perfringens)

Quality Level

type

Type I

form

lyophilized powder

specific activity

10-50 units/mg protein

composition

protein, 20-40%

greener alternative product characteristics

Waste Prevention
Design for Energy Efficiency
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sustainability

Greener Alternative Product

application(s)

diagnostic assay manufacturing

greener alternative category

storage temp.

−20°C

Gene Information

Clostridium perfringens str. 13 ... plc(988262)

General description

我们致力于为您提供更环保的替代产品,以符合“绿色化学的12项原则”的一项或多项原则要求。该产品针对生物柴油研究进行了优化,可提高能效并防止浪费。有关详细信息,请参阅《Biofiles》的文章

Application

磷脂酶 C (PLC) 已被用于研究肾上腺素受体介导的跨膜信号转导。也用于降解含肌醇的磷脂。此外,它还被用于研究 9E3 基因激活

Biochem/physiol Actions

PLC 水解磷脂酰胆碱和其他甘油磷脂上的磷酸键,生成甘油二酯。这种酶也水解鞘磷脂、心磷脂、胆碱缩醛磷脂和神经酰胺磷脂的磷酸键。磷脂酶 C 受凝血酶和血小板活化因子的诱导,形成 1,2-二酰甘油和磷脂酸。
水解磷脂酰胆碱和其他甘油磷脂的磷酸键生成甘油二酯;该酶也可水解鞘磷脂、心磷脂、胆碱缩醛磷脂以及神经酰胺磷脂的磷酸键。

Other Notes

一个单位将在pH 7.3的37 °C下每分钟从蛋黄L-α-磷脂酰胆碱中释放出1.0μmole的水溶性有机磷。


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mojtaba Alimolaei et al.
Probiotics and antimicrobial proteins, 10(2), 251-257 (2017-04-13)
The alpha-toxin is one of the virulence factors of Clostridium perfringens for gas gangrene in humans and animals or necrotic enteritis in poultry. The C-terminal domain of this toxin ( cpa 247-370 ) was synthesized and cloned into pT1NX vector
R Spangler et al.
Proceedings of the National Academy of Sciences of the United States of America, 86(18), 7017-7021 (1989-09-01)
Induction of the transformation-related gene 9E3 by the v-src and v-fps gene products (v-Src and v-Fps) is blocked in chicken embryo fibroblasts depleted of protein kinase C (PKC). PKC agonists induce 9E3 gene expression. Protein kinase inhibitors block v-Src- and
N Sieger et al.
Arthritis and rheumatism, 65(3), 770-779 (2012-12-13)
CD22 is a surface molecule exclusively expressed on B cells that regulates adhesion and B cell receptor (BCR) signaling as an inhibitory coreceptor of the BCR. Central downstream signaling molecules that are activated upon BCR engagement include spleen tyrosine kinase



全球贸易项目编号

货号GTIN
P7633-125UN04061834395706
P7633-25UN04061834395713
P7633-500UN04061832759173