P7936
磷酸肌酸 二钠盐 水合物
≥97%
别名:
N-(亚氨基[膦氨基]甲基)-N-甲基甘氨酸
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关于此项目
线性分子式:
C4H8N3O5PNa2 · x H2O
化学文摘社编号:
分子量:
255.08 (anhydrous basis)
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
213-074-6
MDL number:
产品名称
磷酸肌酸 二钠盐 水合物, ≥97%
Quality Level
assay
≥97%
form
powder
impurities
≤0.02% free creatine
color
white
solubility
water: 50 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
O.[Na+].[Na+].CN(CC(O)=O)C(=N)NP([O-])([O-])=O
InChI
1S/C4H10N3O5P.2Na.H2O/c1-7(2-3(8)9)4(5)6-13(10,11)12;;;/h2H2,1H3,(H,8,9)(H4,5,6,10,11,12);;;1H2/q;2*+1;/p-2
InChI key
KZVYPOKBYRXZKS-UHFFFAOYSA-L
Application
磷酸肌酸二钠盐水合物已用于：
- 作为爪蟾缓冲液(XB)组分，用于去除膜吸附性蛋白质
- 作为M5+缓冲液组分，进行极化全内反射荧光(polTIRF)实验
- 作为ATP再生系统组分，用于7-硝基-2-1,3-苯并噁二唑-4-基磷脂(NBD-PL)转位检测
Biochem/physiol Actions
磷酸肌酸(Phosphocreatine)因其在肌酸激酶作用下的最快再生形式而广为人知，起到临时能量缓冲器的作用。磷酸肌酸存在于肌肉组织中，在维持肌肉细胞的能量稳态中起重要作用。
磷酸肌酸二钠盐水合物可用于研究鼻咽癌细胞和诱发的暂时性心脏骤停。它也用于评估伏隔核中腺苷A(2A)受体调节对大鼠可卡因寻求行为的影响。
磷酸肌酸是脊椎动物和某些无脊椎动物肌肉的高能磷酸基储蓄池，提供ADP-ATP转换所需磷酸。
Preparation Note
酶法制备。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Journal of molecular and cellular cardiology, 49(6), 1031-1041 (2010-08-31)
The Ca(2+) dependent interaction between troponin I (cTnI) and troponin C (cTnC) triggers contraction in heart muscle. Heart failure is characterized by a decrease in cardiac output, and compounds that increase the sensitivity of cardiac muscle to Ca(2+) have therapeutic
Cyril Bernis et al.
Methods in cell biology, 122, 165-191 (2014-05-27)
The large and complex eukaryotic nucleus is the arbiter of DNA replication, RNA transcription, splicing, and ribosome assembly. With the advent of in vitro nuclear reconstitution extracts derived from Xenopus eggs in the 1980s, it became possible to assemble multiple
Protective effects of a magnesium magnetic isotope (Mg(25) )-exchanging nanoparticle ((25) MgPMC(16) ) on mitochondrial functional disorders in esmolol-induced cardiac arrest in rats
Adeli, S., et al.
Auton. Autocoid Pharmacol., 32, 1-7 (2012)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| P7936-1G | 04061834400639 |
| P7936-5G | 04061834400653 |
| P7936-10MG | 04061834400622 |
| P7936-25G | 04061834400646 |