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P9521

21-Deoxycortisol

Name: 21-Deoxycortisol
Brand: SIGMA

synthetic (organic), ≥98.00% (TLC), 17-hydroxyprogesterone derivative, powder

别名:

11β,17α-Dihydroxy-4-pregnene-3,20-dione, 11β,17α-Dihydroxyprogesterone, 21-Desoxycortisol, 4-Pregnene-11β,17α-diol-3,20-dione

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关于此项目

经验公式（希尔记法）:

C₂₁H₃₀O₄

化学文摘社编号:

641-77-0

分子量:

346.46

NACRES:

NA.77

PubChem Substance ID:

24899039

UNSPSC Code:

41116107

EC Number:

211-375-7

MDL number:

MFCD00056476

Assay:

≥98.00% (TLC)

Form:

powder

Quality level:

200

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属性

产品名称

21-Deoxycortisol,

biological source

synthetic (organic)

Quality Level

200

assay

≥98.00% (TLC)

form

powder

solubility

ethanol: 9.80-10.20 mg/mL, clear, colorless

shipped in

ambient

storage temp.

room temp

SMILES string

CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]12C

InChI

1S/C21H30O4/c1-12(22)21(25)9-7-16-15-5-4-13-10-14(23)6-8-19(13,2)18(15)17(24)11-20(16,21)3/h10,15-18,24-25H,4-9,11H2,1-3H3/t15-,16-,17-,18+,19-,20-,21-/m0/s1

InChI key

LCZBQMKVFQNSJR-UJPCIWJBSA-N

说明

Biochem/physiol Actions

21-Deoxycortisol is a 17-hydroxyprogesterone derivative. It serves as a marker for congenital adrenal hyperplasia, an autosomal recessive disorder, indicated by 21-hydroxylase deficiency.

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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A comparison of steroid profiles in the testis and seminal vesicle of the catfish (Heteropneustes fossilis).

Radha Chaube et al.

Theriogenology, 105, 90-96 (2017-09-25)

In the present study, distribution of steroid hormones (estradiol-17β (E

Superior discriminating value of ACTH-stimulated serum 21-deoxycortisol in identifying heterozygote carriers for 21-hydroxylase deficiency

Costa BFA, et al.

Clin. Endocrinol., 73(6), 700-706 (2010)

Apparent activities of 21-hydroxylase, 17alpha-hydroxylase and 17,20-lyase are impaired in adrenal incidentalomas.

J L Sadoul et al.

European journal of endocrinology, 141(3), 238-245 (1999-09-04)

An increased response of 17-hydroxyprogesterone to ACTH stimulation has been observed in adrenal incidentaloma and linked to an impairment of either 21-hydroxylase or of 11beta-hydroxylase activity. To analyse this question further, we investigated the steroidogenic pathways in a series of

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全球贸易项目编号

货号	GTIN
P9521-25MG	04061832851341