主要文件

查看所有文档

R116

利鲁唑

Name: 利鲁唑
Brand: SIGMA

≥98% (HPLC), solid, glutamate release inhibitor

别名:

2-氨基-6-（三氟甲氧基）苯并噻唑

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₈H₅F₃N₂OS

化学文摘社编号:

1744-22-5

分子量:

234.20

UNSPSC Code:

12352200

PubChem Substance ID:

24278006

NACRES:

NA.77

MDL number:

MFCD00210213

Form:

solid

Quality level:

100

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

产品名称

利鲁唑, solid

Quality Level

100

form

solid

originator

Sanofi Aventis

SMILES string

Nc1nc2ccc(OC(F)(F)F)cc2s1

InChI

1S/C8H5F3N2OS/c9-8(10,11)14-4-1-2-5-6(3-4)15-7(12)13-5/h1-3H,(H2,12,13)

InChI key

FTALBRSUTCGOEG-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)
rat ... Scnn1g(24768)

说明

Biochem/physiol Actions

谷氨酸释放抑制剂；抗惊厥

Features and Benefits

该化合物在受体分类和信号转导手册的钾通道页面上有重点介绍。想要浏览手册的其他页面，请单击此处。

该化合物是由赛诺菲安万特开发的。想要浏览其他由制药公司开发的化合物以及已批准药物/候选药物清单，请单击此处。

Still not finding the right product?

Explore all of our products under 利鲁唑

pictograms

GHS06

signalword

Danger

hcodes

H300

pcodes

P301 + P310 + P330

Hazard Classifications

Acute Tox. 2 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases.

Maurizio Anzini et al.

Journal of medicinal chemistry, 53(2), 734-744 (2009-12-03)

A series of amidine, thiourea, and guanidine derivatives of 2-amino-6-(trifluoromethoxy)benzothiazole termed 2, 3, and 4, respectively, and structurally related to riluzole, a neuroprotective drug in many animal models of brain disease, have been synthesized. The biological activity of compounds 2a-e

Predictions and experimental tests of a new biophysical model of the mammalian respiratory oscillator.

Ryan S Phillips et al.

eLife, 11 (2022-07-08)

Previously our computational modeling studies (Phillips et al., 2019) proposed that neuronal persistent sodium current (INaP) and calcium-activated non-selective cation current (ICAN) are key biophysical factors that, respectively, generate inspiratory rhythm and burst pattern in the mammalian preBötzinger complex (preBötC)

Riluzole for the treatment of acute traumatic spinal cord injury: rationale for and design of the NACTN Phase I clinical trial.

Michael G Fehlings et al.

Journal of neurosurgery. Spine, 17(1 Suppl), 151-156 (2012-09-19)

In the immediate period after traumatic spinal cord injury (SCI) a variety of secondary injury mechanisms combine to gradually expand the initial lesion size, potentially leading to diminished neurological outcomes at long-term follow-up. Riluzole, a benzothiazole drug, which has neuroprotective

查看所有相关文献

全球贸易项目编号

货号	GTIN
R116-250MG	04061832093116
R116-25MG	04061836694227
R116-500MG	04061836694241
R1030-200UL	04061836265588