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Merck
CN

RAB0430

人类 ShhN ELISA 试剂盒

for serum, plasma, cell culture supernatants and urine

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关于此项目

NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... SHH(6469)
Input:
sample type cell culture supernatant(s)
sample type serum
sample type urine
sample type plasma
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
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species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable, capture ELISA: suitable

input

sample type cell culture supernatant(s)
sample type serum
sample type urine
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 42 pg/mL
standard curve range: 40.96-10000 pg/mL
(Assay Diluent C), inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8 pg/mL
standard curve range: 40.96-10000 pg/mL
(Assay Diluent B)

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... SHH(6469)

General description

The Human Shh-N (Sonic Hedgehog N Terminus) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human Shh-N in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human ShhN

Application

请参考Protocol了解详情。

Biochem/physiol Actions

Sonic hedgehog (Shh) is a secreted glycoprotein involved in embryonic morphogenic development of several tissues. It has a role in fracture healing and regeneration. In the canonical pathway, the protein associates with its receptor patched (Ptc-1), de-represses smoothened (Smo) and activates the Gli family of transcription factors. Mutations in the Shh pathway have been linked to developmental diseases and cancer. Shh plays a vital role in axon growth and guidance throughout the brain development. Shh stimulates neurite outgrowth by overcoming neurite growth inhibitory environment associated with glial scar.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.


试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书 & 价格

  • ELISA 5X Assay/Sample Diluent Buffer B (Item E1)
    化学品安全说明书

  • ELISA 1X Assay/Sample Diluent Buffer C (Item L)
    化学品安全说明书

  • ELISA Stop Solution (Item I)
    化学品安全说明书

  • ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
    化学品安全说明书

  • 20X Wash Buffer (Item B)
    化学品安全说明书

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

存储类别

10 - Combustible liquids

法规信息

新产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Sonic hedgehog stimulates neurite outgrowth in a mechanical stretch model of reactive-astrogliosis.
Berretta A
Scientific Reports, 6, 21896-21896 (2016)
Expression and Role of Sonic Hedgehog in the Process of Fracture Healing with Aging.
Matsumoto K
In Vivo, 30(2), 99-105 (2016)
Xuqi Li et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 20(16), 4326-4338 (2014-06-21)
Pancreatic cancer is characterized by stromal desmoplasia and perineural invasion (PNI). We sought to explore the contribution of pancreatic stellate cells (PSC) activated by paracrine Sonic Hedgehog (SHH) in pancreatic cancer PNI and progression. In this study, the expression dynamics



全球贸易项目编号

货号GTIN
RAB0430-1KT04061834962533