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关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... STAT3(6774)
mouse ... STAT3(20848)
rat ... STAT3(25125)
mouse ... STAT3(20848)
rat ... STAT3(25125)
Species reactivity:
human, mouse, rat
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human, mouse, rat
technique(s)
ELISA: suitable, capture ELISA: suitable
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... STAT3(6774)
mouse ... STAT3(20848)
rat ... STAT3(25125)
General description
Signal transducers and activators of transcription 3 (STAT3) is a transcription factor that belongs to the family of STAT proteins. The protein contains an Src homology 2 (SH2) domain for protein-protein interactions. STAT3 is activated by phosphorylation on tyrosine 705 by c-Jun N-terminal kinases (JNKs), cytokine receptor-associated kinases, nonreceptor tyrosine kinases, and growth factor receptor tyrosine kinases, in response to growth factors and cytokines. Phosphorylation of STAT3 is important for dimer formation and gene expression. STAT3 mediates the expression of a variety of genes that are involved in cell proliferation and differentiation. It also aids in pro-cancer immunity. The Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA (enzyme-linked immunosorbent assay) is a very rapid, convenient, and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.
The Phospho-Stat3 (pTyr705) ELISA (Enzyme-Linked Immunosorbent Assay) kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates.
Immunogen
Stat3 (pTyr705) synthetic phosphopeptide, Recombinant Human Stat3
Application
Phospho-Stat3 (pTyr705) and pan-Stat3 ELISA Kit has been used in enzyme-linked immunosorbent assay (ELISA) for quantitative measurement of phosphorylated signal transducer and activator of transcription3 (p-STAT3) in liver tissues.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
存储类别
12 - Non Combustible Liquids
法规信息
常规特殊物品
低风险生物材料
此项目有
相关内容
Instructions
Targeting the Hepatocyte Growth Factor Receptor to Overcome Resistance to Targeted Therapies
Embryonic Stem Cell Protocols, 25-60 (2019)
Hyo Jeong Kang et al.
Oncotarget, 8(16), 27263-27276 (2017-05-04)
The non-receptor tyrosine phosphatase SHP2 has scaffolding functions in signal transduction cascades downstream of growth receptors. A recent study suggested that SHP2 acts as a tumor suppressor during hepatocellular carcinoma (HCC) development. Herein we examined whether SHP2 links the HBx-NF-κB
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| RAB0447-1KT | 04061834962625 |
