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关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... IL18(3606)
Input:
sample type cell culture supernatant(s)
sample type urine
sample type plasma
sample type serum
sample type urine
sample type plasma
sample type serum
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type cell culture supernatant(s)
sample type urine
sample type plasma
sample type serum
assay range
inter-assay cv: <10%
intra-assay cv: <12%
sensitivity: 0.5 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... IL18(3606)
General description
该试剂盒中提供的抗体对可检测血清、血浆、细胞培养上清液和尿液中的人 IL-18。白细胞介素-18(IL-18)是一种促炎性细胞因子,在脂肪、肝和骨骼肌等大多数哺乳动物组织中表达。它可作为原 IL-18 产生,其经酶切形成具有信号肽的成熟 IL-18。Il-18 诱导干扰素-γ 介导的 Th1(T 辅助细胞 1)淋巴细胞作用。它控制脂质和葡萄糖的代谢。炎症小体的激活是 IL-18 释放的原因,这是对病毒感染的重要反应。在肾脏和肝脏疾病、糖尿病、动脉粥样硬化、类风湿性关节炎和哮喘等自身免疫性疾病中观察到 IL-18 水平升高。它也与肾功能障碍的发展有关。
Application
人 IL18/白细胞介素-18 ELISA 试剂盒已用于评估巨噬细胞对反式二苯乙烯和三联苯化合物的细胞因子产生。它还已用于分析和测量慢性肾脏病患者尿液中的 IL-18 水平。
仅限研究用途,不可用于诊断。
请参阅随附的一般ELISA试剂盒 操作步骤 (夹心式、竞争性和间接ELISA)
请参阅随附的一般ELISA试剂盒 操作步骤 (夹心式、竞争性和间接ELISA)
Other Notes
本产品提供样本分析证书。
请在批号对应的文本框中输入单词 sample 。
请在批号对应的文本框中输入单词 sample 。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
flash_point_f
Not applicable
flash_point_c
Not applicable
存储类别
10 - Combustible liquids
法规信息
低风险生物材料
常规特殊物品
此项目有
Quantification of Inflammasome Adaptor Protein ASC in Biological Samples by Multiple-Reaction Monitoring Mass Spectrometry
Ulke-Lemee A, et al.
Inflammation, 41(4), 1396-1408 (2018)
Qi Zeng et al.
Cancer immunology research, 6(5), 566-577 (2018-04-15)
Immunosuppressive myeloid-derived suppressive cells (MDSCs) are characterized by their phenotypic and functional heterogeneity. To better define their T cell-independent functions within the tumor, sorted monocytic CD14+CD11b+HLA-DRlow/- MDSCs (mMDSC) from squamous cell carcinoma patients showed upregulated caspase-1 activity, which was associated
Annegret Ulke-Lemée et al.
Inflammation, 41(4), 1396-1408 (2018-06-28)
Inflammation is an integral component of many diseases, including chronic kidney disease (CKD). ASC (apoptosis-associated speck-like protein containing CARD, also PYCARD) is the key inflammasome adaptor protein in the innate immune response. Since ASC specks, a macromolecular condensate of ASC
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| RAB0543-1KT | 04061834963431 |
