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RAB0934

磷酸酪氨酸ALK / ALK酪氨酸激酶受体ELISA试剂盒

Name: 磷酸酪氨酸ALK / ALK酪氨酸激酶受体ELISA试剂盒
Brand: SIGMA

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关于此项目

NACRES:

NA.32

UNSPSC Code:

41116158

Gene information:

human ... ALK(238)

Species reactivity:

human

Storage temp.:

−20°C

Shipped in:

wet ice

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属性

species reactivity

human

technique(s)

ELISA: suitable

assay range

inter-assay cv: <10%
intra-assay cv: <12%

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... ALK(238)

说明

General description

The antibody pair provided in this kit recognizes Human Tyrosine-Phosphorylated-ALK.

Application

请参考Protocol了解详情。

试剂盒组分也可单独购买

产品编号

说明

化学品安全说明书 & 价格

RABHRP6
Phosphotyrosine ELISA HRP-Streptavidin
化学品安全说明书

pictograms

GHS05

signalword

Warning

hcodes

H290

pcodes

P234 - P390

Hazard Classifications

Met. Corr. 1

存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Discovery of (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a macrocyclic inhibitor of anaplastic lymphoma kinase (ALK) and c-ros oncogene 1 (ROS1) with preclinical brain exposure and broad-spectrum potency against ALK-resistant mutations.

Ted W Johnson et al.

Journal of medicinal chemistry, 57(11), 4720-4744 (2014-05-14)

Although crizotinib demonstrates robust efficacy in anaplastic lymphoma kinase (ALK)-positive non-small-cell lung carcinoma patients, progression during treatment eventually develops. Resistant patient samples revealed a variety of point mutations in the kinase domain of ALK, including the L1196M gatekeeper mutation. In

全球贸易项目编号

货号	GTIN
RAB0934-1KT	04061835166916