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关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
rat ... Bdnf(24225)
Input:
sample type plasma
sample type cell culture supernatant(s)
sample type serum sample(s)
sample type cell culture supernatant(s)
sample type serum sample(s)
Species reactivity:
human, rat
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human, rat
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type cell culture supernatant(s)
sample type serum sample(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 12 pg/ml
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
rat ... Bdnf(24225)
General description
脑源性神经营养因子(BDNF)基因定位于人类染色体11p14.1上。该基因编码前体蛋白proBDNF。成熟的BDNF(mBDNF)是通过proBDNF的翻译后切割合成的。
该ELISA抗体对可检测大鼠和人BDNF。其他物种尚未测定。
Application
仅供研究使用。不可用于诊断操作。
详细内容请参阅附件实验方案。
详细内容请参阅附件实验方案。
Biochem/physiol Actions
脑源性神经营养因子(BDNF)参与人类的海马功能和言语情节记忆。BDNF在血管功能中也起着至关重要的作用,并通过特异性受体原肌球蛋白相关激酶B(TrkB)参与血管生成。它参与了阿尔茨海默′病的发病机制。
Other Notes
本产品提供了样品检验报告。请在批号对应的文本框中输入样品一词。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
flash_point_f
Not applicable
flash_point_c
Not applicable
存储类别
10 - Combustible liquids
法规信息
低风险生物材料
常规特殊物品
此项目有
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function.
Egan MF, et al.
Cell, 112(2), 257-269 (2003)
11p14. 1 microdeletions associated with ADHD, autism, developmental delay, and obesity.
Shinawi M, et al.
American Journal of Medical Genetics. Part A, 155(6), 1272-1280 (2011)
Monica Serra et al.
Aging, 11(11), 3851-3863 (2019-06-13)
Aging increases the risk of cancer partly through alterations in the tissue microenvironment. Time-restricted feeding (TRF) is being proposed as an effective strategy to delay biological aging. In the present studies, we assessed the effect of long-term exposure to TRF
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| RAB1138-1KT | 04061834964940 |
