RAB1271
人精氨酸酶1 ELISA
for serum, plasma and cell culture supernatants
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关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... ARG1(383)
Input:
sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type serum
sample type cell culture supernatant(s)
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2.05 ng/mL
standard curve range: 2.048-500 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... ARG1(383)
General description
The gene encoding arginase 1 (ARG1), spanning 10-15kb on genomic DNA, is localized on human chromosome 6q23.2. It consists of eight exons. The protein consists of 322 amino acids and is expressed in the liver, red blood cells, lactating mammalian glands and the kidney.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
Biochem/physiol Actions
Arginase 1 (ARG1) is a liver enzyme involved in the hydrolysis of arginine to form ornithine and urea. In addition to urea cycle, ARG1 is also implicated in various cellular processes, such as macrophage-mediated cytotoxicity and regulation of immune response. The encoded protein is also involved in allergen challenged lungs, in autoimmune inflammation in the central nervous system and in acute liver injury. Deficiency or mutations in the gene leads to a rare urea cycle disorder, argininemia.
Other Notes
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
flash_point_f
Not applicable
flash_point_c
Not applicable
存储类别
10 - Combustible liquids
法规信息
新产品
此项目有
Clinical phenotype, biochemical profile, and treatment in 19 patients with arginase 1 deficiency
Martina Huemer
Journal of inherited metabolic disease, 39 (2016)
Five Novel Mutations in ARG1 Gene in Chinese Patients of Argininemia
Tong-Fei Wu MD
Pediatric Neurology (2013)
Carbon nanotube-based sensing devices for human Arginase-1 detection
S. Baldo
Sensitization of Cancer Cells for Chemo/Immuno/Radio-therapy, 7 (2016)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| RAB1271-1KT | 04061835169054 |