登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式(希尔记法):
C15H18BrN3O3
化学文摘社编号:
分子量:
368.23
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
SR-95531, ≥98% (HPLC), powder
Quality Level
assay
≥98% (HPLC)
form
powder
color
white
solubility
H2O: >10 mg/mL
SMILES string
[Br-].COc1ccc(cc1)-c2ccc(N)[n+](CCCC(O)=O)n2
InChI
1S/C15H17N3O3.BrH/c1-21-12-6-4-11(5-7-12)13-8-9-14(16)18(17-13)10-2-3-15(19)20;/h4-9,16H,2-3,10H2,1H3,(H,19,20);1H
InChI key
GFZHNFOGCMEYTA-UHFFFAOYSA-N
Gene Information
human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)
rat ... Gabra2(29706)
Biochem/physiol Actions
SR-95531 是一种特异性 GABA a 受体拮抗剂,不影响 GABA 转氨酶或谷氨酸脱羧酶活性。
Features and Benefits
这种化合物是神经科学研究的特色产品。点击此处发现更多特色神经科学产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
商品
DISCOVER Bioactive Small Molecules for Neuroscience
Marvin R Diaz et al.
PloS one, 8(1), e55673-e55673 (2013-02-06)
Cerebellar granule cells (CGNs) are one of many neurons that express phasic and tonic GABAergic conductances. Although it is well established that Golgi cells (GoCs) mediate phasic GABAergic currents in CGNs, their role in mediating tonic currents in CGNs (CGN-I(tonic))
Ian Duguid et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(32), 11132-11143 (2012-08-10)
Tonic inhibition is a key regulator of neuronal excitability and network function in the brain, but its role in sensory information processing remains poorly understood. The cerebellum is a favorable model system for addressing this question as granule cells, which
Le Chang et al.
Neuron, 77(3), 559-571 (2013-02-12)
Retinal specializations such as cone-photoreceptor opsin-expression gradients, as found in several vertebrate species, are intuitively considered detrimental to color vision. In mice, the majority of cones coexpress both "blue" and "green" opsin. The coexpression ratio changes along the dorsoventral axis
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| S106-50MG | 04061836846367 |
| S106-10MG | 04061836846350 |
| SAB5200438-100UG | 04061832146386 |
| SAB5200449-100UG | 04061832146492 |
| SAB5200450-100UG | 04061832146508 |
| SAB5200454-100UG | 04061832146546 |
| SAB5200439-100UG | 04061832146393 |
| SAB5200440-100UG | 04061832146409 |
| SAB5200442-100UG | 04061832146423 |
| SAB5200448-100UG | 04061832146485 |
| SAB5200451-100UG | 04061832146515 |
| SAB5200453-100UG | 04061832146539 |