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Merck
CN

S2500

东莨菪内酯

≥99%

别名:

6-甲氧基伞形酮, 7-羟基-6-甲氧基-2H-1-苯并吡喃-2-酮, 7-羟基-6-甲氧基香豆素, 七叶亭-6-甲醚, 东莨菪亭, 东莨菪内酯, 柯阿托酸, 莨菪亭, 钩吻酸

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关于此项目

经验公式(希尔记法):
C10H8O4
化学文摘社编号:
分子量:
192.17
UNSPSC Code:
12171501
NACRES:
NA.28
PubChem Substance ID:
EC Number:
202-171-9
Beilstein/REAXYS Number:
156296
MDL number:
Assay:
≥99%
Quality level:
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Quality Level

assay

≥99%

mp

203-205 °C (lit.)

SMILES string

COc1cc2C=CC(=O)Oc2cc1O

InChI

1S/C10H8O4/c1-13-9-4-6-2-3-10(12)14-8(6)5-7(9)11/h2-5,11H,1H3

InChI key

RODXRVNMMDRFIK-UHFFFAOYSA-N

Gene Information

human ... ACHE(43)

Application

  • Production of Polyphenolic Natural Products by Bract-Derived Tissue Cultures of Three Medicinal Tilia spp.: A Comparative Untargeted Metabolomics Study.:该文通过三种药用椴树的苞片组织培养生产多酚化合物(包括东莨菪内酯)。突出这三种培养物用于生产宝贵天然产物的潜力(Szűcs et al., 2024)。

Biochem/physiol Actions

东莨菪素通过促进 LPL 基因的转录,显著增强脂肪细胞中脂蛋白脂肪酶的活性。它还部分逆转 TNF-α 对 LPL 的抑制作用。
可用于检测氧化爆发期间活性氧物质释放的染料;过氧亚硝酸盐清除剂;乙酰胆碱酯酶抑制剂。


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存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Urs Lahrmann et al.
The New phytologist, 207(3), 841-857 (2015-04-29)
During a compatible interaction, the sebacinoid root-associated fungi Piriformospora indica and Sebacina vermifera induce modification of root morphology and enhance shoot growth in Arabidopsis thaliana. The genomic traits common in these two fungi were investigated and compared with those of
Yoshihiro Suzuki et al.
Journal of immunology (Baltimore, Md. : 1950), 171(11), 6119-6127 (2003-11-25)
Earlier studies, including our own, revealed that activation of mast cells is accompanied by production of reactive oxygen species (ROS) that help to mediate the release of the inflammatory mediators, including histamine and eicosanoids. However, little is known about the
Ae Ra Kim et al.
Phytotherapy research : PTR, 18(1), 1-7 (2004-01-30)
Peroxynitrite (ONOO(-)) is one of cytotoxic species produced by the reaction between superoxide (*O(2) (-)) and nitric oxide (NO). The main aim of this study was to identify ONOO(-) scavenging constituents from herbs. Methanolic extracts derived from one hundred thirty



全球贸易项目编号

货号GTIN
S2500-100MG04061836919153
S2500-1G04061836919177
S2500-10MG04061835327386
S2500-500MG04061836919238
S2500-50MG04061836919252