S6319
盐酸舍曲林 盐酸盐
≥98% (HPLC), Selective serotonin reuptake inhibitor (SSRI), powder
别名:
盐酸舍曲林, (1S,4S)-4-（3,4-二氯苯基）-1,2,3,4-四氢-N-甲基-1-萘胺 盐酸盐
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C17H17NCl2 · HCl
化学文摘社编号:
分子量:
342.69
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
盐酸舍曲林 盐酸盐, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D +33 to +43°, c = 2.0 in methanol
storage condition
desiccated
color
white
solubility
DMSO: >20 mg/mL
SMILES string
ClC1=C(Cl)C=CC([C@H]2C3=C(C=CC=C3)[C@@H](NC)CC2)=C1.[H]Cl
InChI
1S/C17H17Cl2N.ClH/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11;/h2-6,8,10,12,17,20H,7,9H2,1H3;1H/t12-,17-;/m0./s1
InChI key
BLFQGGGGFNSJKA-XHXSRVRCSA-N
Gene Information
Application
在长期准备好的绵羊胎儿中研究了盐酸舍曲林暴露的影响。将其用于糖皮质激素功能测定，研究抗抑郁药对人体糖皮质激素受体功能的影响。
Biochem/physiol Actions
舍曲林抑制血小板功能，显示抗血小板和内皮保护功能。缓解抑郁症，提高心血管疾病患者的生活质量。 也可开处方治疗帕金森病的抑郁症状。
选择性 5-羟色胺再摄取抑制剂，抗抑郁药。
Features and Benefits
该化合物收录于 受体分类和信号转导手册的《生物胺转运体 》页面。想要浏览手册的其他页面， 请单击此处。
这种化合物是ADME毒性研究的特色产品。点击此处发现更多特色ADME毒性产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。
Still not finding the right product?
Explore all of our products under 盐酸舍曲林 盐酸盐
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
商品
Discover Bioactive Small Molecules for ADME/Tox
Thomas Günther et al.
Journal of child and adolescent psychopharmacology, 15(4), 608-618 (2005-09-30)
This study investigated the cognitive side effects of a 6-week course of sertraline treatment on verbal memory and attention in children and adolescents. Children with various anxiety disorders (social phobia, generalized and separation anxiety disorder; n = 28), between 8
Alexander H Glassman et al.
JAMA, 288(6), 701-709 (2002-08-10)
Major depressive disorder (MDD) occurs in 15% to 23% of patients with acute coronary syndromes and constitutes an independent risk factor for morbidity and mortality. However, no published evidence exists that antidepressant drugs are safe or efficacious in patients with
Rafael R Domingues et al.
Toxics, 10(1) (2022-01-21)
Selective serotonin reuptake inhibitors (SSRI) are the most common antidepressant used by pregnant women; however, they have been associated with adverse pregnancy outcomes and perinatal morbidity in pregnant women and animal models. We investigated the effects of two SSRI, fluoxetine
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| S6319-50MG | 04061836957889 |
| S6319-10MG | 04061836957872 |