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S7632

N-Succinyl-Ala-Ala-Val-Ala p-nitroanilide

Name: N-Succinyl-Ala-Ala-Val-Ala p-nitroanilide
Brand: SIGMA

protease substrate

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关于此项目

经验公式（希尔记法）:

C₂₄H₃₄N₆O₉

化学文摘社编号:

108322-03-8

分子量:

550.56

NACRES:

NA.32

PubChem Substance ID:

24899748

UNSPSC Code:

12352204

MDL number:

MFCD00133618

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属性

Quality Level

200

assay

≥98% (TLC)

form

powder

solubility

DMF: 10 mg/mL, clear, colorless

UniProt accession no.

P57774

storage temp.

−20°C

SMILES string

CC(C)C(NC(=O)C(C)NC(=O)C(C)NC(=O)CCC(O)=O)C(=O)NC(C)C(=O)Nc1ccc(cc1)N(=O)=O

InChI

1S/C24H34N6O9/c1-12(2)20(24(37)27-14(4)22(35)28-16-6-8-17(9-7-16)30(38)39)29-23(36)15(5)26-21(34)13(3)25-18(31)10-11-19(32)33/h6-9,12-15,20H,10-11H2,1-5H3,(H,25,31)(H,26,34)(H,27,37)(H,28,35)(H,29,36)(H,32,33)

InChI key

IYHHIHIBYVIDMJ-UHFFFAOYSA-N

Gene Information

mouse ... Npy(109648)

说明

General description

N-Succinyl-Ala-Ala-Val-Ala p-nitroanilide is a chromogenic and a synthetic peptide substrate for proteases, elastase and subtilisin.

Application

N-Succinyl-Ala-Ala-Val-Ala p-nitroanilide has been used as a synthetic peptide substrate for:

Bacillus pumilus alkaline protease (DHAP)
mesophilic subtilisin Carlsberg (sC) to assess the hydrolytic activity of wild-type and mutant sC
Pseudoalteromonas arctica cold-active protease (Pro21717)

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Substrate specificity and thermostability of the dehairing alkaline protease from Bacillus pumilus.

Min-Yuan Wan et al.

Applied biochemistry and biotechnology, 159(2), 394-403 (2009-01-10)

An alkaline protease (DHAP) from Bacillus pumilus has shown great potential in hide dehairing. To get better insights on its catalytic properties for application, the substrate specificity and thermostability were investigated using five natural proteins and nine synthetic peptides. The

A Zingerone Analog, Acetyl Zingerone, Bolsters Matrisome Synthesis, Inhibits Matrix Metallopeptidases, and Represses IL-17A Target Gene Expression.

William R Swindell et al.

The Journal of investigative dermatology, 140(3), 602-614 (2019-08-30)

Zingerone (Z) is a phenolic alkanone derived from natural sources with anti-inflammatory and antioxidant effects. Acetyl zingerone (AZ) is a recently designed molecule that shares structural features with Z but is expected to have improved stability and antioxidant function. This

全球贸易项目编号

货号	GTIN
S7632-25MG	04061832925455