SAB1401666
抗-SLC40A1 兔抗
purified immunoglobulin, buffered aqueous solution
别名:
FPN1, HFE4, IREG1, MST079, MSTP079, MTP1
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
15
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
western blot: 1 μg/mL
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... SLC40A1(30061)
General description
该基因所编码的蛋白是一种可能参与了来自十二指肠上皮细胞铁输出的细胞膜蛋白。该基因的缺陷是4型血色素沉着病（HFE4）的一个诱因。（由RefSeq提供）
Immunogen
SLC40A1 (NP_055400.1, 1 a.a. ~ 571 a.a) 人全长蛋白。
序列
MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLKEEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITPTKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFRFAQNTLGNKLFACGPDAKEVRKENQANTSVV
序列
MTRAGDHNRQRGCCGSLADYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVYGLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKHELLTMYHGWVLTSCYILIITIANIANLASTATAITIQRDWIVVVAGEDRSKLANMNATIRRIDQLTNILAPMAVGQIMTFGSPVIGCGFISGWNLVSMCVEYVLLWKVYQKTPALAVKAGLKEEETELKQLNLHKDTEPKPLEGTHLMGVKDSNIHELEHEQEPTCASQMAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMTVLGFDCITTGYAYTQGLSGSILSILMGASAITGIMGTVAFTWLRRKCGLVRTGLISGLAQLSCLILCVISVFMPGSPLDLSVSPFEDIRSRFIQGESITPTKIPEITTEIYMSNGSNSANIVPETSPESVPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVILAPNPEAFGLLVLISVSFVAMGHIMYFRFAQNTLGNKLFACGPDAKEVRKENQANTSVV
Biochem/physiol Actions
铁转运蛋白-1（FPN1）是一种铁输出蛋白，参与铁从外部和内部位点转移到血液中的过程，从而维持铁稳态。FPN1主要从巨噬细胞和肠细胞输出铁，也会从肝细胞输出铁。FPN1也能将铁从胎盘转运到胎儿体内。FPN1在翻译后受铁调素调节，最终降解。该基因突变会导致铁在巨噬细胞和肠道中积累和亚临床贫血，从而导致铁转运蛋白疾病。
Physical form
溶于pH7.4的磷酸盐缓冲盐水中的溶液
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Still not finding the right product?
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Ferroportin mRNA is down-regulated in granulosa and cervical cells from infertile women.
Moreno-Navarrete JM
Fertility and Sterility, 107(1), 236-242 (2017)
Ironing out Ferroportin.
Drakesmith H
Cell Metabolism, 22(5), 777-787 (2015)
José Maria Moreno-Navarrete et al.
Fertility and sterility, 107(1), 236-242 (2016-11-16)
To explore the relationship between iron and infertility by investigating iron-related gene expression in granulosa and uterine cervical cells. Case-control study. Two tertiary hospitals. Two independent cohorts of fertile (n = 18 and n = 17) and infertile (n =
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB1401666-100UG | 04061831643121 |