biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
form
liquid
mol wt
93 kDa
species reactivity
mouse, bovine, human, rat
concentration
1 mg/mL
technique(s)
ChIP: suitable, immunocytochemistry: suitable, immunofluorescence: suitable, immunohistochemistry: 1:100-1:1000, immunoprecipitation (IP): suitable, western blot: 500-10000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... HIF1A(3091)
Immunogen
包含与 HIF1 alpha 的 657 和 826 位氨基酸相对应的序列的重组片段
Application
建议的起始稀释度如下：ICC/IF：1：100-1：1000，IHC-Fr：稀释度由测定方法确定，IHC-P：1：100-1：1000，IP：1：100-1：570， WB：1：500-1：10000，ChIP 测定法：稀释度由测定方法确定。尚未在其他应用中进行测试。最佳工作稀释液应由终端用户通过实验确定。
Biochem/physiol Actions
缺氧诱导因子-1 （HIF1）是在低氧培养的哺乳动物细胞中发现的一种转录因子，它在对缺氧的细胞和系统体内稳态反应中起着至关重要的作用。HIF1 是由 α 亚基和 β 亚基组成的异二聚体。β 亚基已被确定为芳香烃受体核转位子（ARNT）。该基因编码 HIF-1 的 α 亚基。研究表明，该基因的天然反义转录物（aHIF）的过表达与非乳头状肾癌有关。已经鉴定出编码不同同工型的两个替代转录本。[由 RefSeq 提供]
Features and Benefits
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Physical form
1XPBS，1％BSA，20％ 甘油（pH 7），添加 0.025％ 的 ProClin 300 作为防腐剂。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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signalword
Warning
hcodes
Hazard Classifications
Aquatic Chronic 3 - Skin Sens. 1
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
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Magdalena H Menhofer et al.
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Junhua Mao et al.
American journal of physiology. Renal physiology, 307(9), F1023-F1032 (2014-07-06)
Podocytes play a key role in the formation of cellular crescents in experimental and human diseases. However, the underlying mechanisms for podocytes in promoting crescent formation need further investigation. Here, we demonstrated that mammalian target of rapamycin complex 1 (mTORC1)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB2702132-100UL | 04061837282409 |