SAB3500420
抗-RIPK1 兔抗
affinity isolated antibody, buffered aqueous solution
别名:
抗-RIP, 抗-RIP1, 抗-受体相互作用丝氨酸/苏氨酸蛋白激酶1
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关于此项目
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IF, IHC, WB
Citations:
18
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, rat, mouse
technique(s)
immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... RIPK1(8737)
General description
受体相互作用丝氨酸/苏氨酸蛋白激酶1(RIPK1)基因位于人染色体6p25.2上。属于RIPK家族。RIPK1是一种坏死性凋亡调节蛋白。它由N端激酶结构域、RIP同型相互作用基序和C端死亡结构域组成。
Immunogen
RIPK1抗体通过人RIPK1氨基末端附近的15个氨基酸多肽免疫制取。
Application
兔抗-RIPK1抗体可用于：
- 蛋白质印迹
- 免疫细胞化学
- 免疫荧光
Biochem/physiol Actions
受体相互作用丝氨酸/苏氨酸蛋白激酶1(RIPK1)参与炎症信号转导和促存活(prosurvival)。还参与调节半胱天冬酶8介导的细胞凋亡。RIPK1在活化B细胞核因子κ-轻链增强子(NF-κB)和丝裂原激活蛋白(MAP)激酶的激活中发挥作用。其基因突变与损伤的固有和适应性免疫关联。还可导致极早发型炎症性肠病(VEO-IBDs)。
受体相互作用丝氨酸/苏氨酸蛋白激酶1(RIPK1)可调节细胞生存和死亡。还在炎症中起作用。
Features and Benefits
完放心地使用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多信息。
Physical form
以含有0.02%叠氮化钠的PBS形式提供。
Other Notes
可用封闭肽SBP3500420封闭该抗体作用。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
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Intestinal dysfunction, especially acute pathologies linked to intestinal ischemia/reperfusion (I/R) injury, is profoundly affected by inflammation and improper execution of cell death. Few studies have examined the efficacy of combined strategies in regulated intestinal epithelial necrosis after intestinal I/R. Here
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Evidence-based complementary and alternative medicine : eCAM, 2018, 6719460-6719460 (2018-05-04)
Tauroursodeoxycholic acid (TUDCA) is a kind of hydrophilic bile acid, which could protect cells from death via inhibiting endoplasmic reticulum (ER) stress. However, the role of TUDCA in compression-induced intervertebral disc degeneration (IVDD) has not been elucidated. Here, we used
Nunzia D'Onofrio et al.
FEBS letters, 596(10), 1313-1329 (2022-02-06)
Ergothioneine (Egt) is a dietary amino acid which acts as an antioxidant to protect against ageing-related diseases. We investigated the anti-cancer properties of Egt in colorectal cancer cells (CRC). Egt treatment exerted cytotoxicity in a dose-dependent manner, induced reactive oxygen
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB3500420-100UG | 04061832179575 |