biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified from hybridoma cell culture
antibody product type
primary antibodies
clone
2-28-33, monoclonal
form
buffered aqueous solution
mol wt
~50 kDa
species reactivity
dog, chicken, rat, bovine, monkey, human, mouse
concentration
~1.0 mg/mL
technique(s)
immunoblotting: 0.5 μg/mL using mouse embryo fibroblast NIH-3T3 cells extract, immunofluorescence: 1-2 μg/mL using human foreskin fibroblast HS68 cells, immunohistochemistry: suitable
isotype
IgG1
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TUBB(203068)
mouse ... Tubb3(22152)
General description
小鼠单克隆（小鼠IgG1同种型）抗-β-tubulin抗体衍生于由小鼠骨髓瘤细胞与免疫小鼠的脾细胞融合而产生的2-28-33杂交瘤细胞。微管蛋白也称为TUBB，是微管的主要组成单位。微管由α-微管蛋白和β-微管蛋白的异二聚体组装而成；两者的分子量均约为50 kDa并具有相当的同源性。β-微管蛋白已经鉴定出常用于不同物种的相同细胞类型的五个进化上保守的同种型。
Immunogen
来自紫色球海胆 (海胆)精子轴突的Sarkosyl抵抗带。
Application
抗β-微管蛋白单克隆抗体可用于：
- 免疫印迹
- 免疫荧光
- 免疫组化
Biochem/physiol Actions
单克隆抗-β-tubulin抗体可特异性识别自由生活土壤线虫秀丽隐杆线虫的两种主要β-tubulin同种型和一种次要β-tubulin同种型。它也能够与来自紫色球海胆精子轴突的Sarkosyl抵抗带、玻璃海鞘（海鞘类）幼虫的神经元轴突、拟南芥根尖细胞中的微管以及人、小鼠、大鼠、猴、牛、狗和鸡的β-tubulin发生结合。不同β-tubulin同种型显示出不同的聚合成微管能力。
Physical form
溶于含有 15 mM 叠氮化钠的 0.01M 磷酸盐缓冲盐水（pH 7.4）溶液中。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB4200715-100UL | 04061838026545 |