Anti-Collagen I α2 antibody produced in rabbit

Anti-Collagen I α2 Antibody detects endogenous levels of total Collagen I α2 protein.

Collagen I α2 (COL1A2) is located on human chromosome 7q22.1. Human COL1A2 gene consists of two dinucleotide repeats: one in the 5′-flanking region of the gene, made of of poly(dC–dA) and poly(dC–dG) and the other in the first intron comprised of poly(dG–dT).

The antiserum was produced against synthesized peptide derived from human Collagen I alpha2.

Immunogen Range: 471-520

Anti-Collagen I α2 antibody has been used to quantify protein expression levels after western blotting.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Collagen I α2 (COL1A2) is essential to maintain elasticity of the vessel wall and is an important constituent of the extracellular matrix. Mutations in COL1A2 results in osteogenesis imperfecta (OI).

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Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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