SAB4500366
Anti-Collagen Type II (COL2A1) Antibody
rabbit polyclonal
别名:
II 类型, 胶原蛋白, 胶原蛋白 α-1 (II), 软骨钙素, 钴 2a1
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.43
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, IHC, WB
Citations:
13
产品名称
抗 胶原 II 兔抗, affinity isolated antibody
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 141 kDa
species reactivity
human, mouse, rat
concentration
~1 mg/mL
technique(s)
ELISA: 1:20000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... COL2A1(1280)
General description
抗 胶原 II 抗体检测内源性总胶原 II 蛋白水平。
II型胶原蛋白α1链（COL2A1）基因位于人染色体12q13.11–q13.12。COL2A1属于胶原蛋白超家族。该编码蛋白的特征在于三条相同的α链形成的同型三聚体。II型胶原蛋白是软骨的主要成分。
Immunogen
制备了抗人 II 型胶原合成肽的抗血清。
免疫原范围： 101-150
免疫原范围： 101-150
Biochem/physiol Actions
II 型胶原蛋白α1 链 (COL2A1)突变，导致骨骼发育不良、身材矮小、感官缺陷等多种临床表现，统称为 II 型胶原蛋白病。COL2A1 在关节软骨中的功能是形成高度组织化的纤维，这对组织的机械性质至关重要。
Features and Benefits
完全放心地试用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多。
Physical form
兔 IgG 溶于磷酸盐缓冲盐水（不含 Mg2+ 和 Ca2+），pH7.4，150mM NaCl，0.02％ 叠氮化钠和 50％ 甘油中。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Mouna Barat-Houari et al.
Human mutation, 37(1), 7-15 (2015-10-08)
Mutations in the COL2A1 gene cause a spectrum of rare autosomal-dominant conditions characterized by skeletal dysplasia, short stature, and sensorial defects. An early diagnosis is critical to providing relevant patient care and follow-up, and genetic counseling to affected families. There
Yu Yao et al.
International journal of molecular medicine, 41(1), 173-183 (2017-11-09)
Surgery-obtained synovium specimens (SSSs) can provide a source of synovial mesenchymal stem cells (SMSCs) for experimental studies. However, these specimens contain diverse tissues, including the intima and subintima; therefore, these SMSCs are not entirely derived from the intima and their cell source
Christine I Seidl et al.
Arthritis & rheumatology (Hoboken, N.J.), 68(2), 398-409 (2015-09-12)
To investigate the function of microRNA-138 (miR-138) in human articular chondrocytes (HACs). The expression of miR-138 in intact cartilage and cultured chondrocytes and the effects of miR-138 overexpression on chondrocyte marker genes were investigated. Targets of miR-138 relevant to chondrocytes
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB4500366-100UG | 04061837743894 |