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Merck
CN

SAB4501162

Anti-Glial Fibrillary Acidic Protein Antibody

rabbit polyclonal

别名:

Glial fibrillary acidic protein

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA, IF, IHC, WB
Citations:
13
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产品名称

Anti-GFAP antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 49 kDa

species reactivity

human

concentration

~1 mg/mL

technique(s)

ELISA: 1:1000, immunofluorescence: 1:100-1:500, immunohistochemistry: 1:50-1:100, western blot: 1:500-1:1000

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GFAP(2670)

General description

Anti-GFAP Antibody detects endogenous levels of total GFAP protein.
Glial fibrillary acidic protein (GFAP) is an intermediate-filament protein found in the astrocytes of CNS (central nervous system). It is located on human chromosome 17q21.

Immunogen

The antiserum was produced against synthesized peptide derived from human GFAP.

Immunogen Range: 11-60

Application

Anti-GFAP, N-Terminal antibody has been used in immunocytochemical analysis , confocal and fluorescent microscopic imaging , immunostaining and western blotting.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Biochem/physiol Actions

Glial fibrillary acidic protein (GFAP) regulates intermediate filament network dynamics, cell morphology and focal adhesions.It helps in maintaining myelination and stability of CNS (central nervous system) white matter architecture.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
低风险生物材料

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination
Liedtke W, et al.
Neuron, 17, 607-615 (1996)
Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy
Bordi M, et al.
Autophagy, 12 (2016)
Suppression of agrin-22 production and synaptic dysfunction in Cln1 (-/-) mice
Peng S, et al.
Annals of Clinical and Translational Neurology, 2, 1085-1104 (2015)



全球贸易项目编号

货号GTIN
SAB4501162-100UG04061837744419