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SAB4501821

ANTI-TAU (MAPT) Antibody

Name: ANTI-TAU (MAPT) Antibody
Brand: SIGMA

rabbit polyclonal

别名:

MAPT, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau

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关于此项目

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD00164745

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA, WB

Citations:

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属性

产品名称

Anti-TAU antibody produced in rabbit, affinity isolated antibody

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 78 kDa

species reactivity

mouse, rat, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:20000, western blot: 1:500-1:1000

NCBI accession no.

P10636

UniProt accession no.

P10636

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MAPT(4137)

说明

General description

Anti-TAU antibody detects endogenous levels of total TAU protein.

MAPT (microtubule associated protein tau) is located on human chromosome 17q21.3. It is expressed in neurons but is most prominent in axons.

Immunogen

The antiserum was produced against synthesized peptide derived from human Tau.

Immunogen Range: 501-550

Biochem/physiol Actions

Removal of MAPT results in developmental delay and learning disability. It participates in the pathology of Alzheimer′s disease (AD). It helps in the assembly and maintenance of microtubule structure.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

217237

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Specific detection of Staphylococcus aureus infection and marker for Alzheimer disease by surface enhanced Raman spectroscopy using silver and gold nanoparticle-coated magnetic polystyrene beads.

Robert Prucek et al.

Scientific reports, 11(1), 6240-6240 (2021-03-20)

Targeted and effective therapy of diseases demands utilization of rapid methods of identification of the given markers. Surface enhanced Raman spectroscopy (SERS) in conjunction with streptavidin-biotin complex is a promising alternative to culture or PCR based methods used for such

Microdeletion encompassing MAPT at chromosome 17q21.3 is associated with developmental delay and learning disability

Shaw-Smith C

Nature Genetics, 38(9), 1032-1037 (2006)

The H1c haplotype at the MAPT locus is associated with Alzheimer's disease

Myers AJ, et al.

Human Molecular Genetics, 14(16), 2399-2404 (2005)

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全球贸易项目编号

货号	GTIN
SAB4501821-100UG	04061837744952