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SAB4700303

Monoclonal Anti-HLA-E-Biotin antibody produced in mouse

Name: Monoclonal Anti-HLA-E-Biotin antibody produced in mouse
Brand: SIGMA

clone MEM-E/07, purified immunoglobulin, buffered aqueous solution

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关于此项目

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

biotin conjugate

Clone:

MEM-E/07, monoclonal

Application:

FACS

Citations:

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属性

biological source

mouse

Quality Level

100

conjugate

biotin conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

MEM-E/07, monoclonal

form

buffered aqueous solution

species reactivity

human

concentration

1 mg/mL

technique(s)

flow cytometry: suitable

isotype

IgG1

NCBI accession no.

NM_005516.5

UniProt accession no.

P13747

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... HLA-E(3133)

说明

General description

The antibody MEM-E/07 recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells.

Immunogen

Bacterially expressed recombinant HLA-E refolded with beta2-microglobulin and peptide

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 2 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

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存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品

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分析证书(COA)

Lot/Batch Number

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HLA-E surface expression is independent of the availability of HLA class I signal sequence-derived peptides in human tumor cell lines.

Giulio Lelio Palmisano et al.

Human immunology, 66(1), 1-12 (2004-12-29)

Human leukocyte antigen (HLA)-E is a nonclassic HLA class I molecule whose expression at the cell surface of tumor cells might allow them to escape T- and natural killer (NK)-cell immune surveillance. In this study, we analyzed HLA-E expression in

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货号	GTIN
SAB4700303-100UG	04061829672065