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SAB4700595

Monoclonal Anti-CD154 antibody produced in hamster

Name: Monoclonal Anti-CD154 antibody produced in hamster
Brand: SIGMA

clone MR-1, purified immunoglobulin, buffered aqueous solution

别名:

Anti-CD40L, Anti-Cd40lg

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关于此项目

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

MR-1, monoclonal

Application:

FACS

Citations:

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属性

biological source

hamster

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

MR-1, monoclonal

form

buffered aqueous solution

species reactivity

mouse

concentration

1 mg/mL

technique(s)

flow cytometry: suitable

isotype

IgG1

NCBI accession no.

NM_011616.2

UniProt accession no.

P27548

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

mouse ... Cd40lg(21947)

说明

General description

The hamster monoclonal antibody MR-1 detects mouse CD154 / CD40L (CD40-ligand), a 39 kDa cell surface glycoprotein expressed predominantly on activated CD4+ lymphocytes.

Immunogen

Activated mouse Th1 clone D16

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 4 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品

低风险生物材料

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

523415

522084

G47K

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Misfolding of major histocompatibility complex class I molecules in activated T cells allows cis-interactions with receptors and signaling molecules and is associated with tyrosine phosphorylation.

Susana G Santos et al.

The Journal of biological chemistry, 279(51), 53062-53070 (2004-10-09)

Knowledge of the origin and biochemical status of beta(2)-microglobulin-free or misfolded major histocompatibility complex (MHC)-I molecules is essential for understanding their pleiotropic properties. Here we show that in normal human T cells, misfolding of MHC-I molecules is turned on upon

Simultaneous LFA-1 and CD40 ligand antagonism prevents airway remodeling in orthotopic airway transplantation: implications for the role of respiratory epithelium as a modulator of fibrosis.

Tomohiro Murakawa et al.

Journal of immunology (Baltimore, Md. : 1950), 174(7), 3869-3879 (2005-03-22)

Airway remodeling is a prominent feature of certain immune-mediated lung diseases such as asthma and chronic lung transplant rejection. Under conditions of airway inflammation, the respiratory epithelium may serve an important role in this remodeling process. Given the proposed role

全球贸易项目编号

货号	GTIN
SAB4700595-100UG	04061832716015