产品名称
抗AQP4 兔抗, 1 mg/mL, affinity isolated antibody
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous glycerol solution
mol wt
antigen predicted mol wt 35 kDa
species reactivity
rat, human, mouse
concentration
1 mg/mL
technique(s)
indirect immunofluorescence: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
rat ... Aqp4(25293)
General description
水通道蛋白4（AQP4）在神经系统中表达。蛋白质的基因ID为25293。
Immunogen
C 末端肽
Biochem/physiol Actions
检测 ~35 kDa。可检出较大的糖基化条带 ~50 kDa。
水通道蛋白 4 (AQP4) 在大鼠脑内发挥水通道的作用。
Features and Benefits
完全放心地试用我们的抗体。如果抗体在您的申请的研究中不起作用，我们将全额退款或安排替代抗体。了解更多。
Physical form
PH 7.4 PBS、50%甘油和0.09%叠氮化钠
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
S Ceccariglia et al.
Neuroscience, 274, 273-288 (2014-06-10)
Trimethyltin chloride (TMT) is a neurotoxicant producing neuronal degeneration and reactive astrogliosis in the mammalian central nervous system, especially the hippocampus. A previous magnetic resonance imaging investigation in TMT-treated rats evidenced dilation of lateral ventricles, also suggesting alterations in blood-brain
Alex J Smith et al.
Acta neuropathologica communications, 7(1), 74-74 (2019-05-10)
Redistribution of the water channel aquaporin-4 (AQP4) away from astrocyte endfeet and into parenchymal processes is a striking histological feature in mouse models of Alzheimer's disease (AD) and other neurological conditions with prominent astrogliosis. AQP4 redistribution has been proposed to
Gökhan Akdemir et al.
Neuroscience letters, 574, 70-75 (2014-04-11)
Astrocyte water channel aquaporin-4 (AQP4) facilitates water movement across the blood-brain barrier and into injured astrocytes. We previously showed reduced cytotoxic brain edema with improved neurological outcome in AQP4 knockout mice in water intoxication, infection and cerebral ischemia. Here, we
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SAB5200112-100UL | 04061838059185 |