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SAB5300249

Monoclonal Anti-MLH1 antibody produced in mouse

Name: Monoclonal Anti-MLH1 antibody produced in mouse
Brand: SIGMA

clone 4C9C7, ascites fluid

别名:

COCA2, FCC2, HNPCC

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关于此项目

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

4C9C7, monoclonal

Application:

ELISA (d), IF, IHC, WB

Citations:

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属性

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

4C9C7, monoclonal

mol wt

85 kDa

species reactivity

human, monkey

technique(s)

direct ELISA: 1:10,000, immunohistochemistry: 1:200-1:1,000, indirect immunofluorescence: 1:200-1:1,000, western blot: 1:500-1:2,000

isotype

IgG1

UniProt accession no.

P40692

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MLH1(4292)

说明

Immunogen

Purified recombinant fragment of MLH1 (aa381-483) expressed in E.coli.
Mouse monoclonal antibody raised against MLH1

Physical form

Ascitic fluid containing 0.03% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

PM10010170

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MLH1 and MSH2 mutation screening in HNPCC families of Hungary - Two new MMR gene mutations.

M Tanyi et al.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 40(11), 1445-1452 (2014-08-12)

Hereditary Non-Polyposis Colorectal Cancer is an inherited disease with deleterious germline mutations in the DNA mismatch repair genes causing the development of colon cancer and other malignancies. This is the first study in Hungary screening the population of our colorectal

BRAF-mutated microsatellite stable colorectal carcinoma: an aggressive adenocarcinoma with reduced CDX2 and increased cytokeratin 7 immunohistochemical expression.

Michael S Landau et al.

Human pathology, 45(8), 1704-1712 (2014-06-09)

Reduced CDX2 and cytokeratin 20 (CK20) expression in colorectal carcinoma with BRAF mutation and high-level microsatellite instability (MSI-H) has been well documented. The immunophenotype of BRAF-mutated microsatellite stable (MSS) colorectal carcinoma has not been reported. We analyzed 205 colorectal carcinomas

Lynch Syndrome in patients with clear cell and endometrioid cancers of the ovary.

Koah R Vierkoetter et al.

Gynecologic oncology, 135(1), 81-84 (2014-08-06)

Patients with Lynch Syndrome are at an increased risk for a variety of malignancies, including ovarian cancer. Ovarian cancers associated with Lynch Syndrome are predominantly clear cell or endometrioid in histology. Lynch Syndrome is characterized by germline mutations in mismatch

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全球贸易项目编号

货号	GTIN
SAB5300249-100UL	04061837599309