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SAB5700472

Anti-Phospho-PLCG2-Y1217 antibody produced in rabbit

Name: Anti-Phospho-PLCG2-Y1217 antibody produced in rabbit
Brand: SIGMA

别名:

APLAID, FCAS3, PLC-IV, PLC-gamma-2, PLCG2

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关于此项目

NACRES:

NA.43

UNSPSC Code:

12352203

Clone:

polyclonal

Species reactivity:

mouse, human

Application:

IHC, WB

Citations:

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属性

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

147

species reactivity

mouse, human

concentration

0.37 mg/ml

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 1:500-1:2000

UniProt accession no.

P16885

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr1217)

Gene Information

human ... PLCG2(5336)

说明

General description

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.

Immunogen

A synthetic phosphorylated peptide around Y1217 of human PLCG2 (NP_002652.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c