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SCP0138

BQ-3020

Name: BQ-3020
Brand: SIGMA

别名:

Acetyl-(Ala 11,15)-ET 1 (6-21), Acetyl-[Ala 11,15]-endothelin 1 (6-21), BQ 3020, endothelin receptor agonist

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关于此项目

经验公式（希尔记法）:

C₉₆H₁₄₀N₂₀O₂₅S₁

化学文摘社编号:

143113-45-5

分子量:

2006.32

UNSPSC Code:

12352200

NACRES:

NA.32

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属性

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

UniProt accession no.

P05305

storage temp.

−20°C

SMILES string

S(CC[C@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc5ccc(cc5)O)C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc3[nH]cnc3)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N

InChI

1S/C93H136N20O23S/c1-15-51(9)77(91(133)110-72(93(135)136)40-58-44-96-62-27-21-20-26-61(58)62)113-92(134)78(52(10)16-2)112-89(131)71(43-75(119)120)108-85(127)66(37-49(5)6)105-87(129)69(41-59-45-95-47-98-59)104-79(121)54(12)100-83(125)67(38-56-24-18-17-19-25-56)106-86(128)68(39-57-29-31-60(115)32-30-57)109-90(132)76(50(7)8)111-80(122)53(11)99-73(116)46-97-81(123)63(28-22-23-34-94)102-88(130)70(42-74(117)118)107-82(124)64(33-35-137-14)103-84(126)65(36-48(3)4)101-55(13)114/h17-21,24-27,29-32,44-45,47-54,63-72,76-78,96,115H,15-16,22-23,28,33-43,46,94H2,1-14H3,(H,95,98)(H,97,123)(H,99,116)(H,100,125)(H,101,114)(H,102,130)(H,103,126)(H,104,121)(H,105,129)(H,106,128)(H,107,124)(H,108,127)(H,109,132)(H,110,133)(H,111,122)(H,112,131)(H,113,134)(H,117,118)(H,119,120)(H,135,136)/t51-,52-,53-,54-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,76-,77-,78-/m0/s1

InChI key

NUAGCEFLVCODRQ-KETPNHLCSA-N

Gene Information

human ... EDN1(1906)

说明

Biochem/physiol Actions

BQ-3020, a linear endothelin analog, is a selective ETB endothelin receptor agonist.

pictograms

GHS06

signalword

Danger

hcodes

H300 + H330

pcodes

P260 - P264 - P271 - P284 - P304 + P340 + P310 - P403 + P233

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 1 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

BB0159

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A. Bjorklund

Peptides (New York, NY, United States) (2000)

A novel radioligand [125I]BQ-3020 selective for endothelin (ETB) receptors.

Ihara M

Life Sciences, 51(6) (1992)

Endothelin-1 stimulates human adipocyte lipolysis through the ET A receptor.

A K S Eriksson et al.

International journal of obesity (2005), 33(1), 67-74 (2008-11-05)

Levels of the vascular peptide endothelin-1 (ET-1) are significantly elevated in obesity. Adipose tissue-derived ET-1 attenuates insulin-mediated antilipolysis in human visceral adipocytes through the activation of the ET receptor B (ET(B)R), thereby linking ET-1 to insulin resistance. Whether ET-1 has

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全球贸易项目编号

货号	GTIN
SCP0138-1MG	04061826693520
SCP0138-500UG	04061833025024