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Merck
CN

SML0679

丹参素 钠盐

≥98% (HPLC)

别名:

(R)-α,3,4-三羟基-苯丙酸 钠盐, (R)-(+)-3-(3,4-二羟基苯基)乳酸, 3-(3′,4′-二羟基苯基)-(2R)-乳酸 钠盐, DS 182, 丹参素, 丹参酸 A

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关于此项目

经验公式(希尔记法):
C9H9O5 · Na
化学文摘社编号:
分子量:
220.15
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
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Quality Level

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D +30 to +40°, c = 1 in H2O

color

white to beige

solubility

H2O: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

OC1=C(O)C=CC(C[C@@H](O)C([O-])=O)=C1.[Na+]

InChI

1S/C9H10O5.Na/c10-6-2-1-5(3-7(6)11)4-8(12)9(13)14;/h1-3,8,10-12H,4H2,(H,13,14);/q;+1/p-1/t8-;/m1./s1

InChI key

ZMMKVDBZTXUHFO-DDWIOCJRSA-M

Biochem/physiol Actions

丹参素具有心脏保护作用,可保护心肌免受输液损伤,并通过 Akt 和 ERK1/2 磷酸化抑制 H9c2 心肌细胞凋亡。
丹参素是丹参中的一种活性成分,可抑制活性氧形成,抑制血小板粘附和聚集,避免心肌缺血。丹参素具有心脏保护作用,可保护心肌免受输液损伤,并通过 Akt 和 ERK1/2 磷酸化抑制 H9c2 心肌细胞凋亡。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Libo Du et al.
Nanotoxicology, 7(3), 294-300 (2012-02-09)
To suppress the cytotoxicity of gold nanoparticles (AuNPs), danshensu, a naturally occurring polyphenol antioxidant isolated from Chinese herb, was used to provide a fundamental protection layer for AuNPs, to alleviate oxidative stress and as a reducing agent to react with
Dongwang Zhao et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 29(6), 625-630 (2013-06-12)
A simple, but highly sensitive, electrochemical sensor for the determination of salvianic acid A sodium (SAS) based on reduced graphene oxide (rGO) is reported. The sensor (rGO/GCE(ox)) was prepared by coating an rGO film on the surface of a pre-anodized
Sunisa Seetapun et al.
Bioscience reports, 33(4), doi:10-doi:10 (2013-07-23)
Novel Danshensu derivatives (3-8) were designed and synthesized to improve bioactivity based on the strategy of 'medicinal chemical hybridization'. Our previous studies indicated that these compounds exhibited noticeable cardioprotective activities. Here, we investigate whether these novel Danshensu derivatives exert neuroprotective



全球贸易项目编号

货号GTIN
SML0679-25MG04061832723747
SML0679-5MG04061832723754