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Merck
CN

SML1073

BIX

≥98% (HPLC), molecular chaperone GRP78 inducer, powder

别名:

2-(3,4-二羟基苯基)-2-氧乙基酯硫氰酸, BiP蛋白诱导剂X

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关于此项目

经验公式(希尔记法):
C9H7NO3S
化学文摘社编号:
分子量:
209.22
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
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产品名称

BIX, ≥98% (HPLC)

Quality Level

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

OC1=C(O)C=C(C(CSC#N)=O)C=C1

InChI

1S/C9H7NO3S/c10-5-14-4-9(13)6-1-2-7(11)8(12)3-6/h1-3,11-12H,4H2

InChI key

SVFLBLCWKKQKDW-UHFFFAOYSA-N

Application

BIX已被用于细胞活力检测。

Biochem/physiol Actions

BIX是分子伴侣GRP78(BIP,葡萄糖调节蛋白78)的一种诱导因子。
BIX(BiP蛋白诱导因子X)可诱导内质网伴侣蛋白GRP78(葡萄糖调节蛋白78,BiP)的表达,导致未折叠蛋白应答的减弱。 BIX可保护神经元细胞和视网膜细胞免受内质网应激诱导的细胞死亡。

Other Notes

空气敏感


pictograms

Exclamation mark

signalword

Warning

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1



历史批次信息供参考:

分析证书(COA)

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全球贸易项目编号

货号GTIN
SML1073-25MG04061832724447
SML1073-5MG04061832724454