SML1102
达非那新氢溴酸盐 氢溴酸盐
≥98% (HPLC), Muscarinic antagonist, powder
别名:
UK 88525–04, （3S）-1- [2-（2,3-二氢-5-苯并呋喃基）乙基]-α,α-二苯基-3-吡咯烷乙酰胺 氢溴酸盐
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关于此项目
经验公式（希尔记法）:
C28H30N2O2 · HBr
化学文摘社编号:
分子量:
507.46
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
达非那新氢溴酸盐 氢溴酸盐, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D +41 to +49°, c = 1 in methylene chloride
storage condition
desiccated
color
white to beige
solubility
DMSO: 20 mg/mL, clear
storage temp.
−20°C
SMILES string
O=C(N)C([C@H]1CN(CCC2=CC=C(OCC3)C3=C2)CC1)(C4=CC=CC=C4)C5=CC=CC=C5.Br
InChI
1S/C28H30N2O2.BrH/c29-27(31)28(23-7-3-1-4-8-23,24-9-5-2-6-10-24)25-14-17-30(20-25)16-13-21-11-12-26-22(19-21)15-18-32-26;/h1-12,19,25H,13-18,20H2,(H2,29,31);1H/t25-;/m1./s1
InChI key
UQAVIASOPREUIT-VQIWEWKSSA-N
Gene Information
human ... CHRM2(1129), CHRM3(1131)
General description
达非那新是一种毒蕈碱受体拮抗剂。它是一种缓释片剂，含有7.5 mg或15 mg达非那新氢溴酸盐。
Application
氢溴酸达非那新已被用于实验动物注射。
Biochem/physiol Actions
氢溴酸达非那新是一种解痉挛毒蕈碱拮抗剂，对阻断M3毒蕈碱乙酰胆碱受体具有选择性。
氢溴酸达非那新是一种解痉挛毒蕈碱拮抗剂，对阻断M3毒蕈碱乙酰胆碱受体具有选择性，M3毒蕈碱乙酰胆碱受体主要负责膀胱肌肉的收缩。 氢溴酸达非那新对M3的亲和力分别比M1和M5高9和12倍，对M3的亲和力比M2和M4分别高59倍。 达非那新在临床上可用于治疗尿失禁和膀胱过度活动症。
Features and Benefits
该化合物是神经科学研究推荐产品。点击此处 ，查看更多神经科学精选产品。想要了解有关生物活性小分子在其他研究领域应用的更多信息，请访问 sigma.com/discover-bsm。
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
商品
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML1102-50MG | 04061832077024 |
| SML1102-10MG | 04061837107603 |