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SML3317

Losartan

≥98% (HPLC), powder, angiotensin II receptor type 1 (AT1) antagonist

别名:

1-[1-[[2′-(2H-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-butyl-4-chloro-1H-imidazol-5-yl]methanol, 2-Butyl-4-chloro-1-[[2′-(1H-tetrazol-5-yl)-1,1′-biphenyl-4-yl]methyl]-1H-imidazole-5-methanol, 2-Butyl-4-chloro-1-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol, DUP 89

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关于此项目

经验公式（希尔记法）:
C22H23ClN6O
化学文摘社编号:
114798-26-4
分子量:
422.91
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
MFCD19686114
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
100
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产品名称

Losartan, ≥98% (HPLC)

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

−20°C

SMILES string

OCC1=C(Cl)N=C(CCCC)N1CC2=CC=C(C3=C(C4=NNN=N4)C=CC=C3)C=C2

InChI

1S/C22H23ClN6O/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22/h4-7,9-12,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28)

InChI key

PSIFNNKUMBGKDQ-UHFFFAOYSA-N

Biochem/physiol Actions

Losartan is an orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist. Losartan is used for treatment of hypertension.
Orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Lact. - Repr. 1B - Skin Sens. 1

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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P C Wong et al.
The Journal of pharmacology and experimental therapeutics, 255(2), 584-592 (1990-11-01)
DuP 753 and PD123177 are two nonpeptide angiotensin II (AII)-specific ligands, which show high affinities for two respective and distinct subtypes of AII binding sites, i.e., AII-1 and AII-2 sites, respectively, in the rat adrenal gland, brain and uterus. The

全球贸易项目编号

货号GTIN
SML3317-10MG04065268048160
SML3317-50MG04065268048177