SML3672
Elvitegravir
≥98% (HPLC)
别名:
6-(3-chloro-2-fluorobenzyl)-1-[(S)-1-hydroxymethyl-2-methylpropyl]-7-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, GS 9137, GS-9137, GS9137, JTK 303, JTK-303, JTK303
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关于此项目
经验公式（希尔记法）:
C23H23ClFNO5
化学文摘社编号:
分子量:
447.88
UNSPSC Code:
51111800
NACRES:
NA.25
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D -26 to -34°, c = 0.5 in methanol
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
Fc1c(cccc1Cc2cc3c([n](cc([c]3=O)C(=O)O)[C@H](CO)C(C)C)cc2OC)Cl
InChI
1S/C23H23ClFNO5/c1-12(2)19(11-27)26-10-16(23(29)30)22(28)15-8-14(20(31-3)9-18(15)26)7-13-5-4-6-17(24)21(13)25/h4-6,8-10,12,19,27H,7,11H2,1-3H3,(H,29,30)/t19-/m1/s1
InChI key
JUZYLCPPVHEVSV-LJQANCHMSA-N
Biochem/physiol Actions
Elvitegravir (JTK-303; GS-9137) is an orally active human immunodeficiency virus type 1 (HIV-1) integrase inhibitor that prevents HIV-1 replication (EC50 = 0.9 nM using HTLV-I transformed T4-cell line MT-4) by blocking viral DNA to host DNA strand transfer (IC50 = 7.2 nM by cell-free assays).
Orally active human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML3672-10MG | 04065269082736 |
| SML3672-50MG | 04065269082743 |