T0632
硫代乙醇酸钠
≥96.5% (iodometric)
别名:
巯乙酸 钠盐, 巯基乙酸 钠盐
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关于此项目
线性分子式:
HSCH2COONa
化学文摘社编号:
分子量:
114.10
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
206-696-4
Beilstein/REAXYS Number:
4569109
MDL number:
assay
≥96.5% (iodometric)
form
powder
color
white to off-white
useful pH range
6.7 (20 °C, 100 g/L)
mp
>300 °C (lit.)
solubility
water: ~609.1 g/L at 20 °C (OECD Test Guideline 105)
storage temp.
−20°C
SMILES string
[Na+].[O-]C(=O)CS
InChI
1S/C2H4O2S.Na/c3-2(4)1-5;/h5H,1H2,(H,3,4);/q;+1/p-1
InChI key
GNBVPFITFYNRCN-UHFFFAOYSA-M
Application
巯基乙酸钠用作：
- 用作富集培养基中的生长补充剂，研究其对弓形菌属的影响
- 在流感血凝素制剂中，减少二硫化物介导的交联反应和早期效力损失
- 电子显微镜下
Biochem/physiol Actions
巯基乙酸钠用作还原剂，适用厌氧菌和微需氧菌生长。
巯基乙酸钠是细菌学研究中用来保持培养基还原条件的常用试剂。巯基乙酸还能够通过将蛋白质硫醇基维持在还原状态，保护酶，防止酶失活。巯基乙酸培养基经常用于炎症研究，在体内诱导中性粒细胞和巨噬细胞响应。
Disclaimer
在室温下，在水中浓度超过70%情况下，每月会形成1-2%的硫代乙丙交酯，在酸性或碱性条件下，会水解成原来的自由化合物。70%溶液在空气中氧化，但当密封后在室温下稳定。巯基乙酸盐在储存过程中可能会丧失纯度。去除空气并不会改善稳定度。
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Chronic 3 - Met. Corr. 1 - Skin Sens. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
ppe
dust mask type N95 (US), Eyeshields, Gloves
Improved stability of recombinant hemagglutinin using a formulation containing sodium thioglycolate
Rhodes DG, et al.
Vaccine, 33(44), 6011-6016 (2015)
Romina A Cutrullis et al.
Immunobiology, 222(2), 423-431 (2016-09-04)
The proinflammatory cytokine macrophage migration inhibitory factor (MIF) is a key player in innate immunity. MIF has been considered critical for controlling acute infection by the protozoan Trypanosoma cruzi, but the underlying mechanisms are poorly understood. Our study aimed to
Kim De Paepe et al.
PeerJ, 7, e6293-e6293 (2019-02-01)
Undigestible, insoluble food particles, such as wheat bran, are important dietary constituents that serve as a fermentation substrate for the human gut microbiota. The first step in wheat bran fermentation involves the poorly studied solubilization of fibers from the complex
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T0632-500G | 04061835367993 |
| T0632-100G | 04061835367979 |
| T0632-25G | 04061835367986 |