主要文件

查看所有文档

T3202

Torsemide

Name: Torsemide
Brand: SIGMA

≥98% (HPLC), solid

别名:

Demadex, N-[[(1-Methylethyl)amino]carbonyl]-4-[(3-methylphenyl)amino]-3-pyridinesulfonamide

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₁₆H₂₀N₄O₃S

化学文摘社编号:

56211-40-6

分子量:

348.42

NACRES:

NA.77

PubChem Substance ID:

329826741

UNSPSC Code:

12352200

MDL number:

MFCD00866166

Assay:

≥98% (HPLC)

Form:

solid

Quality level:

100

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

Quality Level

100

assay

≥98% (HPLC)

form

solid

solubility

DMSO: soluble 18 mg/mL, H₂O: insoluble

originator

Roche

SMILES string

CC(C)NC(=O)NS(=O)(=O)c1cnccc1Nc2cccc(C)c2

InChI

1S/C16H20N4O3S/c1-11(2)18-16(21)20-24(22,23)15-10-17-8-7-14(15)19-13-6-4-5-12(3)9-13/h4-11H,1-3H3,(H,17,19)(H2,18,20,21)

InChI key

NGBFQHCMQULJNZ-UHFFFAOYSA-N

Gene Information

human ... SLC12A1(6557)

说明

Application

Torsemide has been used as an inhibitor of Na⁺ Cl^- co-transporter in transgenic Arabidopsis thaliana plants¹.

Biochem/physiol Actions

Torsemide functions in the thick ascending limb of the loop of Henle and enhances the excretion of sodium, chloride and water from the luminal side of the cells. Furthermore, torsemide can treat oedematous conditions that are associated with diseases such as liver cirrhosis, kidney disorders and chronic congestive heart failure².

Torsemide is a loop diuretic and inhibitor of the Na⁺/K⁺/2Cl^-carrier system.

Torsemide is a loop diuretic of the pyridine-sulfonylurea class with antialdosteronergic properties and inhibitor of the Na⁺/K⁺/2Cl^-carrier system.

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Preparation Note

Torsemide is soluble in DMSO at 18 mg/ml and is insoluble in water.

Still not finding the right product?

Explore all of our products under Torsemide

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H319,H361fd

pcodes

P201 - P202 - P264 - P280 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Eye Irrit. 2 - Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

新产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

A9C sensitive Cl⁻-accumulation in A. thaliana root cells during salt stress is controlled by internal and external calcium.

Livia Saleh et al.

Plant signaling & behavior, 8(6), e24259-e24259 (2013-04-23)

The involvement of chloride in salt stress symptoms and salt tolerance mechanisms in plants has been less investigated in the past. Therefore, we studied the salt-induced chloride influx in Arabidopsis expressing the GFP-based anion indicator Clomeleon. High salt concentrations induce

Torasemide. A review of its pharmacological properties and therapeutic potential.

H A Friedel et al.

Drugs, 41(1), 81-103 (1991-01-01)

Torasemide (torsemide) is a high-ceiling loop diuretic which acts on the thick ascending limb of the loop of Henle to promote rapid and marked excretion of water, sodium and chloride. Like furosemide (frusemide), its major site of action is from

Loop diuretic therapy in left ventricular systolic dysfunction: has familiarity bred contempt for a critical but potentially nephrotoxic cardio renal therapy?

Robert J MacFadyen et al.

European journal of heart failure, 12(7), 649-652 (2010-06-26)

查看所有相关文献

全球贸易项目编号

货号	GTIN
T3202-50MG	04061832577524
T3202-10MG	04061832577517