T3516
硫代磺素T
Powder
别名:
硫磺素T, 碱性黄1
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关于此项目
经验公式（希尔记法）:
C17H19ClN2S
化学文摘社编号:
分子量:
318.86
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
219-228-9
MDL number:
Beilstein/REAXYS Number:
3922452
Colour Index Number:
49005
产品名称
硫代磺素T, used as stain for amyloid
Quality Level
form
powder
composition
Dye content, ≥65%
solubility
methanol: 1 mg/mL
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
[Cl-].CN(C)c1ccc(cc1)-c2sc3cc(C)ccc3[n+]2C
InChI
1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1
InChI key
JADVWWSKYZXRGX-UHFFFAOYSA-M
General description
硫黄素T是苯并噻唑类染料，与淀粉样蛋白结合后荧光增强。 硫黄素T已可用于组织学和蛋白质表征。
Application
硫黄素T已被用来鉴别样品中淀粉样纤维的存在。
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Matthew Biancalana et al.
Biochimica et biophysica acta, 1804(7), 1405-1412 (2010-04-20)
Intense efforts to detect, diagnose, and analyze the kinetic and structural properties of amyloid fibrils have generated a powerful toolkit of amyloid-specific molecular probes. Since its first description in 1959, the fluorescent dye Thioflavin-T (ThT) has become among the most
Jian Xiong et al.
Biophysical chemistry, 220, 42-48 (2016-11-20)
The hydrophobic fragment of the Alzheimer's related β-amyloid (Aβ) peptide, Aβ(25-40), aggregates and forms insoluble amyloid fibrils at a rate similar to the full-length peptide. In order to gain insight into the fibrillization of Aβ(25-40) and the ability of the
Pai Peng et al.
Nucleic acids research, 45(2), 541-546 (2016-12-03)
We present a conceptually new reversible nanosensor regulated by a DNA nanoswitch. This system is not only responsive to external stimuli (e.g. ATP) but also can be reversibly switched between 'OFF' and 'ON' states via toehold mediated strand displacement reactions.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T3516-25G | 04061837344510 |
| T3516-5G | 04061837344527 |