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关于此项目
经验公式(希尔记法):
C9H12N2O5S
化学文摘社编号:
分子量:
260.27
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
237-735-3
MDL number:
Assay:
≥98%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
water: 20 mg/mL, clear
Storage temp.:
−20°C
产品名称
4-硫代尿苷, ≥98%
biological source
synthetic (organic)
Quality Level
assay
≥98%
form
powder
solubility
water: 20 mg/mL, clear
storage temp.
−20°C
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=S)NC2=O
InChI
1S/C9H12N2O5S/c12-3-4-6(13)7(14)8(16-4)11-2-1-5(17)10-9(11)15/h1-2,4,6-8,12-14H,3H2,(H,10,15,17)/t4-,6-,7-,8-/m1/s1
InChI key
ZLOIGESWDJYCTF-XVFCMESISA-N
General description
4-硫代尿苷是光反应性尿苷类似物。
Application
4-硫代尿苷可用于标记和分离新生RNA。
Biochem/physiol Actions
4-硫代尿苷可以用于评估新生RNA合成。它还可以增强位点特异性交联。4-硫代尿苷即使在缺乏特异性光活化的情况下也具有稳定性,因此也可以用作光亲和探针。也可以将其整合到RNA中。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Ruijia Wang et al.
Cell reports, 26(10), 2766-2778 (2019-03-07)
Regulation of cleavage and polyadenylation (CPA) affects gene expression and polyadenylation site (PAS) choice. Here, we report that the CPA and termination factor PCF11 modulates gene expression on the basis of gene size. Although downregulation of PCF11 leads to inhibition
Lukas Windhager et al.
Genome research, 22(10), 2031-2042 (2012-04-28)
RNA synthesis and decay rates determine the steady-state levels of cellular RNAs. Metabolic tagging of newly transcribed RNA by 4-thiouridine (4sU) can reveal the relative contributions of RNA synthesis and decay rates. The kinetics of RNA processing, however, had so
Indira Memet et al.
Nucleic acids research, 45(9), 5359-5374 (2017-01-25)
In eukaryotes, the synthesis of ribosomal subunits, which involves the maturation of the ribosomal (r)RNAs and assembly of ribosomal proteins, requires the co-ordinated action of a plethora of ribosome biogenesis factors. Many of these cofactors remain to be characterized in
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T4509-100MG | 04061837346156 |
| T4509-250MG | 04061837346194 |
| T4509-25MG | 04061837346200 |