T7508
丁卡因 盐酸盐
≥99%, Calcium channel blocker
别名:
4-(丁氨基)-苯甲酸-2-(二甲氨基)乙酯, 丁卡因 盐酸盐
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关于此项目
经验公式（希尔记法）:
C15H24N2O2 · HCl
化学文摘社编号:
分子量:
300.82
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥99%
Quality level:
产品名称
丁卡因 盐酸盐, ≥99%
Quality Level
assay
≥99%
solubility
chloroform: soluble 30 parts, alcohol: soluble 40 parts, H2O: soluble mg/mL, acetone: insoluble, benzene: insoluble, diethyl ether: insoluble
SMILES string
Cl.CCCCNc1ccc(cc1)C(=O)OCCN(C)C
InChI
1S/C15H24N2O2.ClH/c1-4-5-10-16-14-8-6-13(7-9-14)15(18)19-12-11-17(2)3;/h6-9,16H,4-5,10-12H2,1-3H3;1H
InChI key
PPWHTZKZQNXVAE-UHFFFAOYSA-N
Gene Information
Application
盐酸丁卡因已用于研究脊髓麻醉的药理作用。盐酸丁卡因也被用作蛋白酶消化缓冲液的组分。
眼用局部麻醉药；用于脊髓麻醉
Biochem/physiol Actions
阻断 Ca2+ 从肌浆网的电压敏感性释放。
Features and Benefits
该化合物在受体分类和信号转导手册的环核苷酸门控（CNG）和超极化激活的环核苷酸门控（HCN）通道页面上有详细描述。想要浏览手册的其他页面， 请单击此处。
该化合物是环核苷酸研究推荐产品。点击此处 ，查看更多环核苷酸精选产品。想要了解有关生物活性小分子在其他研究领域应用的更多信息，请访问 sigma.com/discover-bsm。
Preparation Note
盐酸丁卡因溶于水，浓度为50 mg/mL，得到无色澄清溶液。它也可溶于40份酒精和30份氯仿。但是，它实际上不溶于醚、苯或丙酮。
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - STOT SE 3
target_organs
Central nervous system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
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L Langerman et al.
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A novel approach for increasing the duration of anesthesia after a single subarachnoid injection of a local anesthetic is presented. Tetracaine 1% 0.5 mg/kg was administered in 10% glucose or in lipid solution (iophendylate) in two groups of rabbits via
A M Knight et al.
European journal of immunology, 22(3), 879-882 (1992-03-01)
Recent reports have shown that both exogenous and endogenous mouse mammary tumor viruses (MMTV) can encode superantigens. Transfection and transgenic studies have identified the open reading frame (ORF) present in the 3' long terminal repeat (LTR) as encoding superantigen function.
Quan Wen et al.
Cornea, 32(2), 179-184 (2012-08-08)
Our recent tissue cross-linking studies have raised the possibility of using aliphatic β-nitroalcohols (BNAs) for pharmacologic, therapeutic corneal cross-linking. The present study was performed to determine the permeability of BNAs and to explore the use of permeability-enhancing agents. Ex vivo
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T7508-25G | 04061837373473 |
| T7508-100G | 04061837373282 |
| T7508-5G | 04061837373497 |