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Merck
CN

T7816

单克隆抗 β-微管蛋白 I 小鼠抗

clone SAP.4G5, ascites fluid

别名:

Anti-CDCBM6, Anti-CSCSC1, Anti-M40, Anti-OK/SW-cl.56, Anti-TUBB1, Anti-TUBB5

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
SAP.4G5, monoclonal
Application:
ARR, ELISA (i), ICC, IHC (p), WB
Citations:
183
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

SAP.4G5, monoclonal

mol wt

antigen ~55 kDa

species reactivity

Xenopus, chicken, human, hamster, canine, mouse, bovine, rat

technique(s)

immunocytochemistry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, indirect ELISA: suitable, microarray: suitable, western blot: 1:20,000 using cultured chicken fibroblasts

isotype

IgG1

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TUBB(203068)
mouse ... Tubb4(22153)

General description

微管蛋白是一种分子量为100 kDa 的蛋白,在所有细胞中以两种相似多肽α和ββ的异源二聚体形式存在并组装形成微管。微管的正确组装是细胞有丝分裂、减数分裂、某些形式的细胞器运动、细胞内转运、鞭毛运动和细胞骨架功能等多种细胞功能的必要基础。抗β-微管蛋白 I 单克隆抗体可用于 ELISA 定位β微管蛋白亚型 I,并可用于免疫印迹定位培养的人类和动物细胞。小鼠抗β-微管蛋白 I 抗体与人、大鼠、狗、牛、仓鼠、小鼠、鸡和爪蟾的β微管蛋白 C 末端序列中的表位发生特异性反应

Immunogen

对应于 β-微管蛋白同种型 I 羧基端序列的合成肽,与 BSA 偶联。

Application

抗β-微管蛋白 I 单克隆抗体(稀释度1:4,000) 可用作免疫沉淀和免疫印迹中的一抗。它还可用于蛋白质印迹分析和逆转录病毒感染。

Biochem/physiol Actions

识别一个位于 β-微管蛋白同种型 I 羧基端序列的表位。未观察到与其他微管蛋白同种型的反应。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。


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flash_point_f

Not applicable

flash_point_c

Not applicable

存储类别

12 - Non Combustible Liquids

法规信息

常规特殊物品
动物来源生物产品
动物来源生物产品

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Microtubules of the eukaryotic cytoskeleton are composed of a heterodimer of α- and β-tubulin. In addition to α-and β-tubulin, several other tubulins have been identified, bringing the number of distinct tubulin classes to seven.


A A Atwood et al.
Oncogene, 29(45), 6004-6015 (2010-09-08)
Overexpression of Ras(V12) in MCF10A cells, an immortalized mammary epithelial cell line, leads to transformation of these cells. We demonstrate that this is accompanied by degradation of C/EBPbeta1. C/EBPbeta is a transcription factor in which three protein isoforms exist because
Geza Gemes et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(10), 3536-3549 (2011-03-11)
Painful nerve injury disrupts levels of cytoplasmic and stored Ca(2+) in sensory neurons. Since influx of Ca(2+) may occur through store-operated Ca(2+) entry (SOCE) as well as voltage- and ligand-activated pathways, we sought confirmation of SOCE in sensory neurons from
Ning Zhao et al.
Circulation research, 116(1), 23-34 (2014-10-18)
MicroRNA miR145 has been implicated in vascular smooth muscle cell differentiation, but its mechanisms of action and downstream targets have not been fully defined. Here, we sought to explore and define the mechanisms of miR145 function in smooth muscle cells.



全球贸易项目编号

货号GTIN
T7816-.2ML04061837378652