U0881
尿酸
BioXtra, ≥99% (HPLC)
别名:
2,6,8-三羟基嘌呤
登录 查看组织和合同定价。
选择尺寸
变更视图
关于此项目
经验公式（希尔记法）:
C5H4N4O3
化学文摘社编号:
分子量:
168.11
UNSPSC Code:
12352005
NACRES:
NA.55
PubChem Substance ID:
EC Number:
200-720-7
Beilstein/REAXYS Number:
156158
MDL number:
Assay:
≥99% (HPLC)
Biological source:
animal (seabird feces (guano))
Form:
powder
Solubility:
1 M NaOH: soluble 50 mg/mL, clear, faintly yellow
biological source
animal (seabird feces (guano))
Quality Level
product line
BioXtra
assay
≥99% (HPLC)
form
powder
impurities
≤0.005% Phosphorus (P)
ign. residue
≤0.1%
mp
>300 °C (lit.)
solubility
1 M NaOH: soluble 50 mg/mL, clear, faintly yellow
cation traces
Al: ≤0.005%, Ca: ≤0.01%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.05%, Mg: ≤0.001%, NH4+: ≤0.05%, Na: ≤0.1%, Pb: ≤0.001%, Zn: ≤0.0005%
SMILES string
O=C1NC(=O)C2=C(N1)NC(=O)N2
InChI
1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)
InChI key
LEHOTFFKMJEONL-UHFFFAOYSA-N
General description
尿酸是人类嘌呤降解的最终产物。它是由黄嘌呤氧化酶对黄嘌呤的作用形成。尿酸水平升高在临床上表现为痛风。在除人类以外的物种中，尿酸可进一步代谢。在除灵长类动物以外的哺乳动物中，尿酸可转化为尿囊素。在硬骨鱼中，尿囊素可进一步转化为尿囊酸盐，然后水解成尿素和乙醛酸。尿酸还可用于嘌呤的生物合成。它已被研究用作过氧亚硝基等生物自由基的清除剂。已有相关文献发表了关于尿酸的高效液相色谱（HPLC）和气相色谱-质谱（GC-MS）法。尿酸可促进血管平滑肌细胞中单核细胞趋化蛋白-1（MCP-1）的表达。
Application
尿酸已用于：
- 制备尿酸钠（MSU）结晶，以研究其对核定位富含亮氨酸重复序列1（NLRP1）基因表达的影响
- 还原剂，以测试其对正铁肌红蛋白形成的保护能力
- 制备MSU，以研究其作为Clec12a特异性配体的用途。
Still not finding the right product?
Explore all of our products under 尿酸
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
商品
Uric acid present in animal sera impacts serum-supplemented classical cell culture systems, influencing cell culture performance.
Jeremy A Hirota et al.
Respirology (Carlton, Vic.), 19(6), 881-890 (2014-05-17)
Airway epithelial cells represent the first line of defence against inhaled insults, including air pollution. Air pollution can activate innate immune signalling in airway epithelial cells leading to the production of soluble mediators that can influence downstream inflammatory cells. Our
Francesca Viazzi et al.
Pediatrics, 132(1), e93-e99 (2013-06-19)
Hyperuricemia has been shown to be a strong correlate of hypertension in children. However, the complex interaction between serum uric acid (UA), systemic blood pressure (BP), and possibly confounding factors has been elucidated only in part. We evaluated office BP
S F Seys et al.
Allergy, 70(2), 187-194 (2014-11-02)
Daily intensive exercise by elite athletes can result in exercise-induced asthma especially in elite swimmers and this may be linked to epithelial damage. To study airway epithelial damage and release of damage-associated molecular patterns (DAMPs) after intensive exercise in elite
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| U0881-100G | 04061837403866 |
| U0881-10G | 04061837403873 |
| U0881-25G | 04061837403880 |