WH0007442M1
单克隆抗-TRPV1 小鼠抗
clone 1F5, purified immunoglobulin, buffered aqueous solution
别名:
抗-DKFZp434K0220, 抗-VR1, 抗-瞬时受体电位阳离子通道，亚族V，成员1
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关于此项目
Conjugate:
unconjugated
Clone:
1F5, monoclonal
Application:
ELISA (i), WB
Citations:
9
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
1F5, monoclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: suitable, western blot: 1-5 μg/mL
isotype
IgG1κ
GenBank accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TRPV1(7442)
General description
基因编码瞬时受体电位阳离子通道，亚族V，成员1（TRPV1）定位到人类染色体17p13。它是非选择性阳离子通道。该蛋白在气道神经纤维上表达。它也在感觉神经元中强烈表达。
Immunogen
TRPV1（NP_542437, 21 a.a.~ 124 a.a）带有GST标签的部分重组蛋白。仅GST标签的MW为26 KDa。
序列
CPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFPVDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFEAVAQ
序列
CPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFPVDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFEAVAQ
Biochem/physiol Actions
瞬时受体电位阳离子通道亚家族V成员1（TRPV1）是辣椒素受体。它参与疼痛感知。TRPV1还调节传入信号和支气管收缩。在大脑中，它调节神经元功能、运动行为和神经炎症。辣椒素在TRPV1的激活中起着重要作用。
Physical form
溶于pH7.4的磷酸盐缓冲盐水中的溶液
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
低风险生物材料
常规特殊物品
此项目有
The 57 kb deletion in cystinosis patients extends into TRPV1 causing dysregulation of transcription in peripheral blood mononuclear cells.
Freed KA
Journal of medical Genetics (2011)
TRPV1 on astrocytes rescues nigral dopamine neurons in Parkinson's disease via CNTF.
Nam JH
Brain (2015)
Role of transient receptor potential vanilloid 1 in the modulation of airway smooth muscle tone and calcium handling.
Yocum GT
American Journal of Physiology. Lung Cellular and Molecular Physiology (2017)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| WH0007442M1-100UG | 04061832750200 |