X4376
黄嘌呤氧化酶 来源于牛奶
lyophilized powder, 0.4-1.0 units/mg protein
别名:
XOD, 木糖：氧氧化还原酶
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关于此项目
化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-657-6
MDL number:
EC 号:
1.17.3.2.
Specific activity:
0.4-1.0 units/mg protein
Biological source:
bovine milk
biological source
bovine milk
Quality Level
form
lyophilized powder
specific activity
0.4-1.0 units/mg protein
mol wt
283 kDa
composition
Protein, 10.0-25.0%
storage temp.
2-8°C
General description
Formerly E.C.1.1.3.22
Application
来自牛奶的黄嘌呤氧化酶已被用作生成超氧化物的来源。它也已用作内部校准电化学连续酶测定（internally calibrated electrochemical continuous enzyme assay，ICECEA）中的模型酶。
Biochem/physiol Actions
黄嘌呤氧化酶可用作氧化应激的潜在生物标记。它还涉及组织和血管损伤，例如肝损伤、炎症性疾病和慢性心力衰竭。
异黄酮染料木素在0.1-4.0 μM的浓度范围内显示出对黄嘌呤氧化酶的抑制，高于5 μM的浓度则会激活黄嘌呤氧化酶。
木糖氧化酶是一种含钼酶，存在于细胞质中，能够被黄酮类化合物有效抑制。它在一些药物和嘌呤嘧啶代谢中有重要作用。它被认为是活性氧簇的生物来源。
Physical form
含有0.5％的水杨酸钠。
Analysis Note
双缩脲法测蛋白
Other Notes
在pH7.5,25℃条件下，一个单位可每分钟将1.0 μmole黄嘌呤转化为尿酸。以次黄嘌呤为底物可获得约50％的活性。
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signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
低风险生物材料
此项目有
Genistein effect on xanthine oxidase activity.
Sumbayev VV.
Food And Chemical Toxicology, 73, 39-43 (2001)
Resistance of postharvest biocontrol yeasts to oxidative stress: a possible new mechanism of action
Castoria R, et al.
Phytopathology, 93(5), 564-572 (2003)
Massimiliano Magro et al.
Materials (Basel, Switzerland), 13(7) (2020-04-16)
Generally, enzyme immobilization on nanoparticles leads to nano-conjugates presenting partially preserved, or even absent, biological properties. Notwithstanding, recent research demonstrated that the coupling to nanomaterials can improve the activity of immobilized enzymes. Herein, xanthine oxidase (XO) was immobilized by self-assembly
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| X4376-25UN | 04061837549694 |
| X4376-50UN | 04061837549700 |
| X4376-5UN | 04061837549717 |