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Merck
CN

Z0153

ZM 241385

≥98% (HPLC), adenosine A2A antagonist, powder

别名:

4-(-2-[7-氨基-2-{2-呋喃基}{1,2,4}三唑并{2,3-a}{1,3,5}三嗪-5-基-氨基]乙基)苯酚

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关于此项目

经验公式(希尔记法):
C16H15N7O2
化学文摘社编号:
分子量:
337.34
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
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产品名称

ZM 241385, ≥98% (HPLC)

Quality Level

assay

≥98% (HPLC)

form

powder

color

white to tan

solubility

DMSO: >15 mg/mL

storage temp.

room temp

SMILES string

Nc1nc(NCCc2ccc(O)cc2)nc3nc(nn13)-c4ccco4

InChI

1S/C16H15N7O2/c17-14-20-15(18-8-7-10-3-5-11(24)6-4-10)21-16-19-13(22-23(14)16)12-2-1-9-25-12/h1-6,9,24H,7-8H2,(H3,17,18,19,20,21,22)

InChI key

PWTBZOIUWZOPFT-UHFFFAOYSA-N

Biochem/physiol Actions

ZM 241385是一种有效的选择性腺苷A2A拮抗剂。
ZM 241385是一种有效的选择性腺苷A2A拮抗剂。A2A受体可在调节心肌耗氧量和冠状动脉血流中起作用,并在脑中高度表达,并在此发挥重要的谷氨酸和多巴胺释放调节作用。 ZM 241385具有神经保护作用,正被研究用于帕金森病和其他神经退行性疾病。

Features and Benefits

《受体分类和信号转导》手册的 腺苷受体页有该化合物的介绍。想要浏览手册的其他页面, 请单击此处


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

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