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53301-U

Ascentis® Express Peptide ES-C18, 2.7μm HPLC 色谱柱

L × I.D. 5 cm × 2.1 mm, pk of 1 ea

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关于此项目

UNSPSC Code:
41115700
NACRES:
SB.52
eCl@ss:
32110501
L × i.d.:
5 cm × 2.1 mm
Matrix active group:
C18 (octadecyl) phase
Pore size:
160 Å
Matrix:
Fused-Core particle platform, superficially porous particle
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material

stainless steel column

Quality Level

100

agency

suitable for USP L1

product line

Ascentis®

feature

endcapped: no

packaging

pk of 1 ea

manufacturer/tradename

Ascentis®

parameter

≤100 °C temp. range, 600 bar max. pressure (9000 psi)

technique(s)

HPLC: suitable, LC/MS: suitable, UHPLC-MS: suitable, UHPLC: suitable

L × I.D.

5 cm × 2.1 mm

surface area

90 m2/g

impurities

<5 ppm metals

matrix

Fused-Core particle platform, superficially porous particle

matrix active group

C18 (octadecyl) phase

pore size

160 Å

operating pH range

1-9

separation technique

reversed phase

General description

Ascentis Express Peptide ES-C18 色谱柱是专为分离肽和小分子蛋白等高分子量化合物而设计的。这些色谱柱含有先进的熔融核心颗粒，这些颗粒具有较大的孔隙（标准 Ascentis Express 中的 160Å与 90Å），与立体保护的 C18 配体结合，以提供极低 pH 值 (<1) 和高温（高达 100ºC）下的额外稳定性 (ES)。这大大扩展了 Ascentis Express 色谱柱的应用范围。

Legal Information

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
USUE001655
USUE001654
USUE001653
USUE001652
USUE001647

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商品

Ascentis® Express Peptide ES-C18 U/HPLC Columns

Choose Ascentis® Express Peptide ES-C18 U/HPLC Columns based on Fused-Core® technology for fast and efficient separation of high-molecular weight compounds, such as peptides and small proteins. With a 2.7 µm particle size and rigorous testing, these columns offer reliable results and high efficiency.

Meiyun Shi et al.
Journal of separation science, 38(8), 1351-1357 (2015-01-30)
The pentapeptide thymopentin (Arg-Lys-Asp-Val-Tyr, RKDVY) corresponds to amino acids 32-36 of the 49 amino acid immunomodulatory polypeptide, thymopoietin, whose biological activity is partially reproduced. Thymopentin is widely used in the clinic and represents a promising target for drug design but
E Lesellier
Journal of chromatography. A, 1266, 34-42 (2012-11-03)
The recent introduction of new stationary phases for liquid chromatography based on superficially porous particles, called core-shell or fused-core, dramatically improved the separation performances through very high efficiency, due mainly to reduced eddy diffusion. However, few studies have evaluated the
C Gröer et al.
Journal of pharmaceutical and biomedical analysis, 100, 393-401 (2014-09-15)
Cytochrome P450 (CYP) enzymes and UDP-glucuronosyltransferases (UGT) are major determinants in the pharmacokinetics of most drugs on the market. To investigate their impact on intestinal and hepatic drug metabolism, we developed and validated quantification methods for nine CYP (CYP1A2, CYP2B6

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货号GTIN
53301-U04061838530493