53314-U
Ascentis® Express Peptide ES-C18, 2.7μm HPLC 色谱柱
L × I.D. 15 cm × 3 mm, pk of 1 ea
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UNSPSC Code:
41115700
NACRES:
SB.52
eCl@ss:
32110501
L × i.d.:
15 cm × 3 mm
Particle size:
2.7 μm
Matrix active group:
C18 (octadecyl) phase
Pore size:
160 Å
Matrix:
Fused-Core particle platform, superficially porous particle
material
stainless steel column
Quality Level
agency
suitable for USP L1
product line
Ascentis®
feature
endcapped: no
packaging
pk of 1 ea
manufacturer/tradename
Ascentis®
parameter
≤100 °C temp. range, 600 bar max. pressure (9000 psi)
technique(s)
HPLC: suitable, LC/MS: suitable, UHPLC-MS: suitable, UHPLC: suitable
L × I.D.
15 cm × 3 mm
surface area
90 m2/g
impurities
<5 ppm metals
matrix
Fused-Core particle platform, superficially porous particle
matrix active group
C18 (octadecyl) phase
particle size
2.7 μm
pore size
160 Å
operating pH range
1-9
separation technique
reversed phase
General description
Ascentis Express Peptide ES-C18 色谱柱是专为分离肽和小分子蛋白等高分子量化合物而设计的。这些色谱柱含有先进的熔融核心颗粒，这些颗粒具有较大的孔隙（标准 Ascentis Express 中的 160Å与 90Å），与立体保护的 C18 配体结合，以提供极低 pH 值 (<1) 和高温（高达 100ºC）下的额外稳定性 (ES)。这大大扩展了 Ascentis Express 色谱柱的应用范围。
Legal Information
Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
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Choose Ascentis® Express Peptide ES-C18 U/HPLC Columns based on Fused-Core® technology for fast and efficient separation of high-molecular weight compounds, such as peptides and small proteins. With a 2.7 µm particle size and rigorous testing, these columns offer reliable results and high efficiency.
Meiyun Shi et al.
Journal of separation science, 38(8), 1351-1357 (2015-01-30)
The pentapeptide thymopentin (Arg-Lys-Asp-Val-Tyr, RKDVY) corresponds to amino acids 32-36 of the 49 amino acid immunomodulatory polypeptide, thymopoietin, whose biological activity is partially reproduced. Thymopentin is widely used in the clinic and represents a promising target for drug design but
E Lesellier
Journal of chromatography. A, 1266, 34-42 (2012-11-03)
The recent introduction of new stationary phases for liquid chromatography based on superficially porous particles, called core-shell or fused-core, dramatically improved the separation performances through very high efficiency, due mainly to reduced eddy diffusion. However, few studies have evaluated the
C Gröer et al.
Journal of pharmaceutical and biomedical analysis, 100, 393-401 (2014-09-15)
Cytochrome P450 (CYP) enzymes and UDP-glucuronosyltransferases (UGT) are major determinants in the pharmacokinetics of most drugs on the market. To investigate their impact on intestinal and hepatic drug metabolism, we developed and validated quantification methods for nine CYP (CYP1A2, CYP2B6
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 53314-U | 04061838530578 |