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Merck
CN

53848-U

Ascentis® Express 90Å C8 (2.7 μm) HPLC Columns

L × I.D. 5 cm × 3 mm, HPLC Column

别名:

Core-shell (SPP) Fused Core C8 HPLC column

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关于此项目

UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
5 cm × 3 mm
Particle size:
2.7 μm
Matrix active group:
C8 (octyl) phase
Pore size:
90 Å
Matrix:
Fused-Core particle platform, superficially porous particle
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产品名称

Ascentis ® Express C8,2.7μm HPLC 色谱柱, 2.7 μm particle size, L × I.D. 5 cm × 3 mm

material

stainless steel column

Quality Level

agency

suitable for USP L7

product line

Ascentis®

feature

endcapped

manufacturer/tradename

Ascentis®

packaging

1 ea of

parameter

60 °C temp. range, 600 bar max. pressure (9000 psi)

technique(s)

HPLC: suitable, LC/MS: suitable, UHPLC-MS: suitable, UHPLC: suitable

L × I.D.

5 cm × 3 mm

surface area

135 m2/g

impurities

<5 ppm metals

matrix

Fused-Core particle platform, superficially porous particle

matrix active group

C8 (octyl) phase

particle size

2.7 μm

pore size

90 Å

operating pH range

2-9

application(s)

food and beverages

separation technique

reversed phase

General description

通过使用Fused-Core® 粒子技术,Ascentis Express HPLC色谱柱在保持较低的反压力的同时,可以为您提供2μm以下颗粒的高速和高效率。高效率和低背压的结合可使UPLC® (或其他超高压系统)用户,以及常规HPLC用户受益。
访问 Ascentis Express 主页,以获得有关此新色谱柱技术的更多信息。

Application


  • Recent trends in ultra-fast HPLC: new generation superficially porous silica columns: This review explores advancements in high-performance liquid chromatography (HPLC), specifically focusing on the Ascentis® Express C8 column. Highlighting its role in achieving high-efficiency separations due to its design, this column is ideal for rapid, high-resolution chromatographic analysis in pharmaceutical, environmental, and material science applications (Ali et al., 2012).

  • Quality by design approach for the separation of naproxcinod and its related substances by fused core particle technology column: This research employs the Ascentis® Express C8 column, utilizing its high-efficiency and rapid separation capabilities to analyze naproxcinod and its impurities. The study exemplifies the column′s use in pharmaceutical quality control, ensuring drug purity and safety (Inugala et al., 2013).

Legal Information

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.
UPLC is a registered trademark of Waters


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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商品

When a C18 doesn′t give the desired separation, or your sample contains compounds that are known to be difficult to retain or resolve on a C18, consider changing to an Ascentis® Express C8 column.


Ugandar Reddy Inugala et al.
Journal of chromatographic science, 51(5), 453-459 (2012-10-13)
This paper describes the development of a rapid, novel, stability-indicating gradient reversed-phase high-performance liquid chromatographic method and associated system suitability parameters for the analysis of naproxcinod in the presence of its related substances and degradents using a quality-by-design approach. All
Sreenivasa Rao Chitturi et al.
Journal of pharmaceutical and biomedical analysis, 55(1), 31-47 (2011-02-15)
This paper proposes a simple and selective RP-HPLC method for the determination of process impurities and degradation products (degradants) of atazanavir sulfate (ATV) drug substance. Chromatographic separation was achieved on Ascentis(®) Express C8, (150mm×4.6mm, 2.7μm) column thermostated at 30°C under
Federica Pellati et al.
Journal of pharmaceutical and biomedical analysis, 81-82, 126-132 (2013-05-07)
A closed-vessel microwave-assisted extraction (MAE) technique was optimized for the first time for the extraction of polyphenols from raw propolis. The results obtained by means of response surface experimental design methodology showed that the best global response was reached when



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货号GTIN
53848-U04061838534422