grade
pharmaceutical primary standard
API family
acetylcholine
manufacturer/tradename
USP
mp
146-150 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
[Cl-].CC(=O)OCC[N+](C)(C)C
InChI
1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1
InChI key
JUGOREOARAHOCO-UHFFFAOYSA-M
Gene Information
human ... CHRM3(1131)
General description
本产品按照发行药典的发行和规定提供。支持本产品的所有信息，包括安全数据表和任何产品信息传单，都是在发行药典的授权下开发和发布的。如需进一步信息和支持，请访问现行药典网站。
Application
氯化乙酰胆碱USP参考标准品的预期用途是USP规定的指定质量测试和分析。
也用于下列USP专论方法：
也用于下列USP专论方法：
- 滴眼液用氯化乙酰胆碱
- 氯化乙酰甲胆碱
Biochem/physiol Actions
氯化乙酰胆碱，20mg/kg体重注射，减少小鼠实验性诱发脓毒病的死亡和血浆促炎细胞因子。类胆碱能抗-炎症机制可能通过乙酰胆碱和 α7n单核细胞，巨噬细胞和中性粒细胞上的胆红素受体互作接待，降低了促炎细胞活素，比如 TNF-α,IL-1β,和IL-6。
胆碱能突触中的内源性神经递质，通过增强肌膜动作电位来触发肌肉收缩反应。
Analysis Note
这些产品仅供测试和化验使用。它们不适用于人类或动物，也不能用于诊断、治疗或治愈任何类型的疾病。
Other Notes
可能适用相应的销售限制。
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存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Eliane Proulx et al.
Cellular and molecular life sciences : CMLS, 71(7), 1225-1244 (2013-10-15)
Cholinergic modulation of prefrontal cortex is essential for attention. In essence, it focuses the mind on relevant, transient stimuli in support of goal-directed behavior. The excitation of prefrontal layer VI neurons through nicotinic acetylcholine receptors optimizes local and top-down control
Sulan Luo et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 28(4), 1842-1853 (2014-01-09)
This study was performed to discover and characterize the first potent α3β2-subtype-selective nicotinic acetylcholine receptor (nAChR) ligand. A novel α4/7-conotoxin, α-CTxLvIA, was cloned from Conus lividus. Its pharmacological profile at Xenopus laevis oocyte-expressed rat nAChR subtypes was determined by 2-electrode
Kazutaka Kamiya et al.
American journal of ophthalmology, 158(1), 179-184 (2014-04-05)
To evaluate the factors affecting the long-term regression after posterior chamber phakic intraocular lens (Visian ICL; STAAR Surgical) implantation for myopia. Retrospective observational case series. We retrospectively examined 60 eyes of 35 consecutive patients (age, 38.4 ± 9.3 years [mean
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 1008501-200MG | 04061838664525 |