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1044006

USP

阿司匹林

Name: 阿司匹林
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

乙酰水杨酸, 2-乙酰氧基苯甲酸, O-乙酰水杨酸, ASA, 阿司匹林

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关于此项目

线性分子式:

2-(CH₃CO₂)C₆H₄CO₂H

化学文摘社编号:

50-78-2

分子量:

180.16

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329749073

MDL number:

MFCD00002430

Beilstein/REAXYS Number:

779271

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属性

grade

pharmaceutical primary standard

API family

aspirin

manufacturer/tradename

USP

mp

134-136 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CC(=O)Oc1ccccc1C(O)=O

InChI

1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)

InChI key

BSYNRYMUTXBXSQ-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742), PTGS2(5743)

说明

General description

本品按现行药典规定交付。所有为支持本产品而提供的信息，包括SDS和任何产品信息单均由药典颁发机构制定并发布。如需进一步信息和支持，请访问现行药典网站。

Application

阿司匹林USP 参考标准品适用于指定 USP 药典质量测试和分析。

还可根据美国药典（USP）以下规定的专论，配制杂质分析和性能试验用标准溶液：

卡立普多和阿司匹林片剂。
阿司匹林片剂。
阿司匹林丸剂。
布他比妥、阿司匹林、咖啡因和磷酸可待因胶囊。

Biochem/physiol Actions

通过抑制环氧化酶(前列腺素H合酶)，对COX-1亚型具有更高的选择性，阻止前列腺素的产生。抗血栓作用是由于COX-1在血小板中的抑制作用，阻止血栓形成和血小板聚集。对结直肠及其他实体肿瘤有化学预防作用。

Analysis Note

这些产品仅供测试和分析使用。它们不适用于人类或动物的给药，不可用于诊断、治疗或治愈任何疾病。

Other Notes

可能适用相应的销售限制。

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pictograms

GHS07

signalword

Warning

存储类别

11 - Combustible Solids

flash_point_f

482.0 °F

flash_point_c

250 °C

hcodes

H302,H412

pcodes

P264 - P270 - P273 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The physiologic and histologic properties of the distal internal thoracic artery and its subdivisions.

Gideon Sahar et al.

The Journal of thoracic and cardiovascular surgery, 149(4), 1042-1050 (2015-04-25)

We compared the flow rates, reactivity, and morphology of the distal internal thoracic artery and its branches, the superior epigastric and musculophrenic arteries, to test their applicability as possible conduits in coronary artery bypass grafting surgeries. Skeletonized internal thoracic artery

6- versus 24-month dual antiplatelet therapy after implantation of drug-eluting stents in patients nonresistant to aspirin: the randomized, multicenter ITALIC trial.

Martine Gilard et al.

Journal of the American College of Cardiology, 65(8), 777-786 (2014-12-03)

The currently recommended duration of dual antiplatelet therapy (DAPT) in drug-eluting stent (DES) recipients is 12 months to reduce the risk of late stent thrombosis, particularly in those with acute coronary syndrome (ACS). This study hypothesized that antiplatelet treatment with DAPT

Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.

Yasuo Ikeda et al.

JAMA, 312(23), 2510-2520 (2014-11-18)

Prevention of atherosclerotic cardiovascular diseases is an important public health priority in Japan due to an aging population. To determine whether daily, low-dose aspirin reduces the incidence of cardiovascular events in older Japanese patients with multiple atherosclerotic risk factors. The

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全球贸易项目编号

货号	GTIN
1044006-500MG	04061838671769