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1075305

USP

Bisdesmethoxycurcumin

Name: Bisdesmethoxycurcumin
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione

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关于此项目

经验公式（希尔记法）:

C₁₉H₁₆O₄

化学文摘社编号:

33171-05-0

分子量:

308.33

MDL number:

MFCD03419284

UNSPSC Code:

41116107

NACRES:

NA.24

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属性

grade

pharmaceutical primary standard

API family

curcumin

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

Oc1ccc(cc1)\C=C\C(=O)CC(=O)\C=C\c2ccc(cc2)O

InChI

1S/C19H16O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-12,20-21H,13H2/b11-5+,12-6+

InChI key

PREBVFJICNPEKM-YDWXAUTNSA-N

说明

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Bisdesmethoxycurcumin USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Curcuminoids
Curcuminoids Capsules
Curcuminoids Tablets
Powdered Turmeric
Powdered Turmeric Extract
Turmeric

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Bisdemethoxycurcumin suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways.

Ying-Bo Li et al.

Pharmacological reports : PR, 65(3), 700-709 (2013-08-21)

Bisdemethoxycurcumin (BDMC) is a natural derivative of curcumin present in the phenolic components extracted from the dried rhizome of Curcuma longa L. BDMC demonstrated potential chemotherapeutic activities but the underlying mechanisms have not been fully clarified. In the present study

Curcumins promote monocytic gene expression related to β-amyloid and superoxide dismutase clearance.

J R Cashman et al.

Neuro-degenerative diseases, 10(1-4), 274-276 (2011-12-14)

Neurodegenerative diseases are associated with accumulation of modified proteins or peptides including amyloid-β (Aβ) in Alzheimer's disease (AD), and misfolded superoxide dismutase-1 (SOD-1) in amyotrophic lateral sclerosis (ALS). Clearance of Aβ or SOD-1 by the innate immune system may be

The hypomethylation agent bisdemethoxycurcumin acts on the WIF-1 promoter, inhibits the canonical Wnt pathway and induces apoptosis in human non-small-cell lung cancer.

Y-L Liu et al.

Current cancer drug targets, 11(9), 1098-1110 (2011-09-22)

Hypermethylation of the Wnt inhibitory factor-1 (WIF-1) promoter has been implicated in the overactivation of the Wnt pathway in human lung cancer. Curcuminoids exert anti-cancer effects and have been reported to act as hypomethylating agents. Previously, we have investigated and

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全球贸易项目编号

货号	GTIN
1075305-30MG	04061838675248